Abstract
Pulp capping treatment is an endodontic treatment that aims to maintain the vitality of the pulp. Beta-tricalcium phosphate (β-TCP) has a chemical composition close to the structure of bones and teeth that can stimulate odontoblast to form dentin bridge. β-TCP can be obtained from anadara granosa hydrothermal process. This research intends to determine the effect of β-TCP encapsulation of anadara granosa clamshell against IL-10 and TGF β expression in dentin reparative formation. Thirty-six male Wistar rats were divided into six groups: control group (-), no-treatment group, CaOH group, and treatment with β-TCP. Application of pulp capping material on the M1 upper right tooth of Wistar rats that had been prepared for class I cavities. After seven days and 14 applications, the rats were euthanized, the prepared teeth were taken, and then IL-10 and TGFβ were examined. The data were then analyzed statistically (p<0.05). The analyzed data showed significant differences in each group.
Original language | English |
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Pages (from-to) | 1522-1528 |
Number of pages | 7 |
Journal | Journal of International Dental and Medical Research |
Volume | 15 |
Issue number | 4 |
Publication status | Published - 2022 |
Keywords
- Calsium hydroxide
- Il-10
- Pulp capping
- Tgfβ
- Β-tcp