This study aimed to measure the analgesic effect of ethanol extract of Zingiber cassumunar Roxb. rhizome on mice induced by acetic acid. This study was an experimental study with post-test only control design using writhing test method. The sample of the study consisted of 25 mice which were divided into 3 treated groups of Zingiber cassumunar Roxb. extract; P1, P2, and P3, with dosage of 100 mg/kgBW, 200 mg/kgBW, 400 mg/kgBW respectively, a negative control of distilled water (K-), and a positive control of aspirin (K+). The result showed that (P1) and (P2) significantly decreased the number of the writhing in mice compared to (K-) (p<0,05), with percentage of writhing protection of 49,53% and 57,01%, while (P3) group did not show any analgesic activity. Zingiber cassumunar Roxb. extract of 100 mg/kgBW and 200 mg/kgBW showed the insignificant result of pain inhibition compared to the (K+).
|Translated title of the contribution||The Analgesic Effect of Zingiber cassumunar Roxb. Ethanol Extract on Mice using Writhing Test Method|
|Number of pages||6|
|Journal||Jurnal Medik Veteriner|
|Publication status||Published - Apr 2020|
- ethanol extract
- writhing test
- Zingiber cassumunar Roxb