Dry mechanosynthesis and characterization of carbonate apatite based on Indonesian natural sources

Herlina Damayanti, Kristanto Wahyudi, Karlina Noordiningsih, Ayu Ratnasari, Devi Rianti

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


Synthetic carbonate apatite is generally used in bone tissue engineering because of their similar chemical composition with the inorganic component of hard tissue. In natural hard tissue, apatite is supplemented by tracing ions such as carbonate. Carbonate apatite is more bioactive than stoichiometric hydroxyapatite. In this study, carbonate apatite powders were prepared by dry mechanosynthesis method, the powder mixture of hydroxyapatite (HA) powders from Center for Ceramic based on Indonesian limestone and carbonate sources came from CaCO3 (Cirebon origin) and MgCO3. The synthesized results were characterized by X-ray diffraction (XRD), X-ray fluorescence (XRF), Fourier-transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The dry mechanosynthesis method produced carbonate apatite, which is formed by a solid-solid reaction between hydroxyapatite and carbonate sources. The XRD patterns peaks around 31.6 - 33° confirmed the formation of the apatite phase. Based on FTIR spectra, the mixture of HA and MgCO3 forms type B of carbonate apatite as predominant and type A is not dominant. SEM image shows that the particles have an irregular shape with interconnected agglomeration between fine particles to form large particles. Hence, dry mechanosynthesis is a simple method to produce carbonate apatite from Indonesian natural sources. Moreover, this method can reduce waste and cost during production.

Original languageEnglish
Title of host publication4th International Seminar on Chemistry
EditorsYuly Kusumawati, Adi Setyo Purnomo
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735441002
Publication statusPublished - 24 Jun 2021
Event4th International Seminar on Chemistry, ISoC 2021 - Surabaya, Indonesia
Duration: 7 Oct 20208 Oct 2020

Publication series

NameAIP Conference Proceedings
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616


Conference4th International Seminar on Chemistry, ISoC 2021


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