Differences in The Number of Platelets Before and After Being Processed in the Blood Donation Unit of the Indonesian Red Cross in Lumajang Regency

Introduction: The quality of the platelet concentrate is influenced by the number of platelets in it, because a high platelet count is required for the treatment of the patient. The manufacturing process is carried out by centrifugation. Centrifugation is a process used to convert whole blood into platelets, which can increase the number and concentration of platelets. Therefore, this study aims to determine the difference in the number of platelets counted before and after processing. Material and Methods: Samples were taken 4 every month from January to August 2020 using the probability sampling method. So the number of samples used is 32. Processing into concentrated platelets using the centrifugation method Results: Platelets count before treatment was 305,69/µl of blood with a minimum of 281,000/µl and a maximum of 355,000/µl and standard deviation of 19,544. After processing, mean platelet count of 1,067, 31/ µl, Minimum 978,000/ µl, and a maximum of 1,218,000/ µl and standard deviation of 65,863 was obtained. the data were tested for normality using Kolmogorov-Smirnov, the results were 0.060 and the posttest data was 0.179. This shows that the data is normally distributed because the result is > 0.05. Then a paired T test was carried out with the result of 0.000 meaning that there was a difference in the number of platelets before and after processing. Conclusion: The results showed that there were differences in the number of platelets before processing compared to after processing.