TY - JOUR
T1 - Dialysis Membranes for Acute Kidney Injury
AU - Raharjo, Yanuardi
AU - Abidin, Muhammad Nidzhom Zainol
AU - Ismail, Ahmad Fauzi
AU - Fahmi, Mochamad Zakki
AU - Saiful,
AU - Elma, Muthia
AU - Santoso, Djoko
AU - Haula’, Hamizah
AU - Habibi, Ahlan Riwahyu
N1 - Funding Information:
Acknowledgments: The authors express gratitude to DRPM (Directorate of Research and Community Service, Deputy for Strengthening Research and Development, Ministry of Research and Technology/National Research and Innovation) Indonesia’s Research, Grant no: 498/UN3.15/PT/2021, for research funding and facilities.
Funding Information:
Funding: This research was funded by Ministry of Research and Technology/National Research and Innovation of Indonesia, grant number 498/UN3.15/PT/2021.
Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/3
Y1 - 2022/3
N2 - Mortality and morbidity rates among critically ill septic patients having acute kidney injury (AKI) are very high, considering the total number of deaths after their admission. Inappropriate selection of the type of continuous renal replacement therapy and inadequate therapy become the immediate causes of these issues. Dialysis is a commonly used treatment intended to prolong the life of AKI patients. Dialysis membranes, which are the core of dialysis treatment, must be properly selected to ensure fair treatment to the patients. The accumulation of certain types of molecules must be dealt with using the right membrane. Whether it is low-flux, high-flux, or adsorptive type, the dialysis membrane should be chosen depending on the condition of the patients. The selection of dialysis membranes should also be based on their effect on the treatment outcomes and well-being. All these options are needed to serve the patients of different clinical settings. The use of dialysis membranes is not restricted to conventional haemodialysis, but rather they can be employed in haemoperfusion, haemofiltration, haemodiafiltration, or a combination of any two of them. This review focuses in-depth on different types of dialysis membranes, their characteristics, and approaches in addressing the issues encountered in patients having AKI with sepsis and/or multiorgan failure in intensive care units.
AB - Mortality and morbidity rates among critically ill septic patients having acute kidney injury (AKI) are very high, considering the total number of deaths after their admission. Inappropriate selection of the type of continuous renal replacement therapy and inadequate therapy become the immediate causes of these issues. Dialysis is a commonly used treatment intended to prolong the life of AKI patients. Dialysis membranes, which are the core of dialysis treatment, must be properly selected to ensure fair treatment to the patients. The accumulation of certain types of molecules must be dealt with using the right membrane. Whether it is low-flux, high-flux, or adsorptive type, the dialysis membrane should be chosen depending on the condition of the patients. The selection of dialysis membranes should also be based on their effect on the treatment outcomes and well-being. All these options are needed to serve the patients of different clinical settings. The use of dialysis membranes is not restricted to conventional haemodialysis, but rather they can be employed in haemoperfusion, haemofiltration, haemodiafiltration, or a combination of any two of them. This review focuses in-depth on different types of dialysis membranes, their characteristics, and approaches in addressing the issues encountered in patients having AKI with sepsis and/or multiorgan failure in intensive care units.
KW - acute kidney injury
KW - adsorption
KW - haemodialysis membrane
KW - haemoperfusion
KW - mixed matrix membrane
UR - http://www.scopus.com/inward/record.url?scp=85127023277&partnerID=8YFLogxK
U2 - 10.3390/membranes12030325
DO - 10.3390/membranes12030325
M3 - Review article
AN - SCOPUS:85127023277
SN - 2077-0375
VL - 12
JO - Membranes
JF - Membranes
IS - 3
M1 - 325
ER -