TY - JOUR
T1 - Diabetes dance of persadia 1 effect on blood IL-6 level
AU - Pratiwi, W. N.
AU - Purwanto, B.
AU - Abdurachman,
N1 - Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2019/1/7
Y1 - 2019/1/7
N2 - Diabetes dance of Persadia 1 is the evolvement of prior diabetes dance series with aerobic principle and belong to weight bearing exercise with eccentric movement. The aim is to analyze the effect of Diabetes dance of Persadia 1 on blood level of IL-6.16 subjects of healthy housewifes who was participated and divided on 2 groups, exercise group and control group. Exercise group was given with diabetes dance of Persadia 1, 3 times per week, while control group have the unstructured activity. Blood level of IL-6 has been measured from each subject's blood that has taken after 24 hours post single bout exercise (acute-AE) and after repeated exercise (chronic exercise-CE). Paired t-test analysis on both acute (p = 0.674) and chronic (p = 0.949) shows blood level of IL-6 increase on control group post test result, though its not significant, while it has been decrease significantly on exercise group both AE (p = 0.000) and CE (p = 0.000). This happen because the stimulation of endogenous antioxidant production that is gluthatione, thus lowering oxidative stress biomarkers by suppressing H 2 O 2 production, resulting in NFkB inhibition. NFkB inhibition will decrease the production of IL-6 muscle. This study shows that diabetes dance of Persadia 1 is not increasing blood levels of IL-6.
AB - Diabetes dance of Persadia 1 is the evolvement of prior diabetes dance series with aerobic principle and belong to weight bearing exercise with eccentric movement. The aim is to analyze the effect of Diabetes dance of Persadia 1 on blood level of IL-6.16 subjects of healthy housewifes who was participated and divided on 2 groups, exercise group and control group. Exercise group was given with diabetes dance of Persadia 1, 3 times per week, while control group have the unstructured activity. Blood level of IL-6 has been measured from each subject's blood that has taken after 24 hours post single bout exercise (acute-AE) and after repeated exercise (chronic exercise-CE). Paired t-test analysis on both acute (p = 0.674) and chronic (p = 0.949) shows blood level of IL-6 increase on control group post test result, though its not significant, while it has been decrease significantly on exercise group both AE (p = 0.000) and CE (p = 0.000). This happen because the stimulation of endogenous antioxidant production that is gluthatione, thus lowering oxidative stress biomarkers by suppressing H 2 O 2 production, resulting in NFkB inhibition. NFkB inhibition will decrease the production of IL-6 muscle. This study shows that diabetes dance of Persadia 1 is not increasing blood levels of IL-6.
UR - http://www.scopus.com/inward/record.url?scp=85060180732&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/1146/1/012014
DO - 10.1088/1742-6596/1146/1/012014
M3 - Conference article
AN - SCOPUS:85060180732
SN - 1742-6588
VL - 1146
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
IS - 1
M1 - 012014
T2 - 5th International Conference on Advanced Molecular Bioscience and Biomedical Engineering 2018, ICAMBBE 2018
Y2 - 3 September 2018 through 4 September 2018
ER -