Introduction: Compliance for taking medication has become an important activity for patients with hypertension. Compliance is needed to control blood pressure and prevent complications. The purpose of this study was to analyse determinant drug adherence on grade two and three patients with hypertension. Methods: The study design was a descriptive survey using a cross-sectional approach. the sample was 225 patients with hypertension grade two and three. The sampling technique was done using a multistage random sampling technique. The coping strategy is the independent variable and drug adherence is the dependent variable. The research instrument was in the form of a questionnaire which consisted of demographic, coping strategy used, COPE inventory scale questionnaire, and drug adherence using the Hypertension Self-Care Profile questionnaire. Data analysis was performed using the Pearson test and linear regression. Results: The results showed that patient adherence in taking medicine was 51.1% in the medium category. Factors influencing the adherence were ages (p-value: 0.002), return to religion (p-value: 0.011), gender (p-value: 0.016) and suppressing competition activities (p-value: 0.063). Conclusion: Age, gender, return to religion and suppressing competition activities influence the taking of medication in patients with grade two and grade three hypertension. Strengthening coping strategies with transporting to coping emotions is very important and will affect drug adherence in patients with grade two and grade three hypertension.
- coping strategic
- drug adherence