Cytotoxic constituent in the fruit peel of lansium domesticum

Q. Labibah, K. N.W. Tun, N. S. Aminah, A. N. Kristanti, R. Ramadhan, Y. Takaya, C. A.C. Abdullah, M. J. Masarudin

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Phytochemical study of the hexane fruits peel extract of Lansium domesticum contributed to the discovery of onoceranoid-type triterpene, onoceradienedione 1. The structure of the isolated compound was done by advance spectroscopic techniques, comprising IR, UV, 1D, 2D NMR and HR-ESI-MS spectra data. Moreover, hexane extract and isolated compound 1 were examined for their cytotoxic activity against HeLa, T47D, and A549 cells. The results revealed the significance cytotoxic activity in the hexane extract.

Original languageEnglish
Pages (from-to)1336-1340
Number of pages5
JournalRasayan Journal of Chemistry
Volume14
Issue number2
DOIs
Publication statusPublished - 1 Apr 2021

Keywords

  • Anticancer
  • Cytotoxicity
  • Fruit peel
  • Meliaceae
  • Onoceranoid-type triterpene
  • Spectroscopic analysis

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