TY - JOUR
T1 - Current Strategies for Tracheal Decellularization
T2 - A Systematic Review
AU - Jiwangga, Dhihintia
AU - Mahyudin, Ferdiansyah
AU - Mastutik, Gondo
AU - Juliana,
AU - Meitavany, Estya Nadya
N1 - Publisher Copyright:
© 2024 Dhihintia Jiwangga et al.
PY - 2024
Y1 - 2024
N2 - The process of decellularization is crucial for producing a substitute for the absent tracheal segment, and the choice of agents and methods significantly influences the outcomes. This paper aims to systematically review the efficacy of diverse tracheal decellularization agents and methods using the PRISMA flowchart. Inclusion criteria encompassed experimental studies published between 2018 and 2023, written in English, and detailing outcomes related to histopathological anatomy, DNA quantification, ECM evaluation, and biomechanical characteristics. Exclusion criteria involved studies related to 3D printing, biomaterials, and partial decellularization. A comprehensive search on PubMed, NCBI, and ScienceDirect yielded 17 relevant literatures. The integration of various agents and methods has proven effective in the process of tracheal decellularization, highlighting the distinct advantages and drawbacks associated with each agent and method.
AB - The process of decellularization is crucial for producing a substitute for the absent tracheal segment, and the choice of agents and methods significantly influences the outcomes. This paper aims to systematically review the efficacy of diverse tracheal decellularization agents and methods using the PRISMA flowchart. Inclusion criteria encompassed experimental studies published between 2018 and 2023, written in English, and detailing outcomes related to histopathological anatomy, DNA quantification, ECM evaluation, and biomechanical characteristics. Exclusion criteria involved studies related to 3D printing, biomaterials, and partial decellularization. A comprehensive search on PubMed, NCBI, and ScienceDirect yielded 17 relevant literatures. The integration of various agents and methods has proven effective in the process of tracheal decellularization, highlighting the distinct advantages and drawbacks associated with each agent and method.
UR - http://www.scopus.com/inward/record.url?scp=85185575241&partnerID=8YFLogxK
U2 - 10.1155/2024/3355239
DO - 10.1155/2024/3355239
M3 - Review article
AN - SCOPUS:85185575241
SN - 1687-8787
VL - 2024
JO - International Journal of Biomaterials
JF - International Journal of Biomaterials
M1 - 3355239
ER -