Curcumin

Maria L.A.D. Lestari, Gunawan Indrayanto

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

318 Citations (Scopus)

Abstract

Curcumin and its two related compounds, that is, demethoxycurcumin and bis-demethoxycurcumin (curcuminoids) are the main secondary metabolites of Curcuma longa and other Curcuma spp. Curcumin is commonly used as coloring agent as well as food additive; curcumin has also shown some therapeutic activities. This review summarizes stability of curcumin in solutions, spectroscopy characteristics of curcumin (UV, IR, Raman, MS, and NMR), polymorphism forms, method of analysis in both of biological and nonbiological samples, and metabolite studies of curcumin. For analysis of curcumin and its related compounds in complex matrices, application of LC-MS/MS is recommended.

Original languageEnglish
Title of host publicationProfiles of Drug Substances, Excipients and Related Methodology
PublisherAcademic Press Inc.
Pages113-204
Number of pages92
DOIs
Publication statusPublished - 2014

Publication series

NameProfiles of Drug Substances, Excipients and Related Methodology
Volume39
ISSN (Print)1871-5125

Keywords

  • Analysis
  • Chromatography
  • Curcuma spp.
  • Curcumin
  • Metabolism
  • Polymorphism
  • Spectroscopy
  • Stability

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