TY - JOUR
T1 - Covid-19 and Fungal Infection
T2 - A literature review
AU - Darmadi, Darmadi
AU - Pakpahan, Cennikon
AU - Surja, Sem Samuel
N1 - Publisher Copyright:
© 2023, Pakistan Medical Association. All rights reserved.
PY - 2023
Y1 - 2023
N2 - Fungal infections have emerged as a significant and potentially lethal complication in critically ill patients with Covid-19. Infections caused by Aspergillus, Candida, and Mucormycetes, are a common cause of morbidity and mortality in critically ill patients, especially those with preexisting comorbidities. The underlying mechanisms that predispose fungal infections are not fully understood, but the use of corticosteroids, underlying conditions, prolonged hospitalization, and antibiotic are several factors that might be associated. They are associated with higher mortality rates, increased healthcare costs, delayed recovery, and prolonged hospitalization. Antifungal therapy for COVID-19-associated fungal infections can interact with other drugs used to treat COVID-19, which can complicate management. The emergence of antifungal resistance is a concern for the management of COVID-19-associated fungal infections.
AB - Fungal infections have emerged as a significant and potentially lethal complication in critically ill patients with Covid-19. Infections caused by Aspergillus, Candida, and Mucormycetes, are a common cause of morbidity and mortality in critically ill patients, especially those with preexisting comorbidities. The underlying mechanisms that predispose fungal infections are not fully understood, but the use of corticosteroids, underlying conditions, prolonged hospitalization, and antibiotic are several factors that might be associated. They are associated with higher mortality rates, increased healthcare costs, delayed recovery, and prolonged hospitalization. Antifungal therapy for COVID-19-associated fungal infections can interact with other drugs used to treat COVID-19, which can complicate management. The emergence of antifungal resistance is a concern for the management of COVID-19-associated fungal infections.
KW - Pulmonary aspergillosis
KW - coronavirus
KW - invasive candidiasis
KW - mucormycosis
UR - http://www.scopus.com/inward/record.url?scp=85171386890&partnerID=8YFLogxK
U2 - 10.5455/rmj.20230507085024
DO - 10.5455/rmj.20230507085024
M3 - Review article
AN - SCOPUS:85171386890
SN - 0303-5212
VL - 48
SP - 795
EP - 798
JO - Rawal Medical Journal
JF - Rawal Medical Journal
IS - 3
ER -