TY - JOUR
T1 - Corticosteroid therapy for brain tumor patients with adrenal insufficiency
AU - Haq, Irwan Barlian Immadoel
AU - Aprianto, Dirga Rachmad
AU - Susilo, Rahadian Indarto
AU - Wahyuhadi, Joni
N1 - Publisher Copyright:
© 2021 Irwan Barlian Immadoel Haq, Dirga Rachmad Aprianto, Rahadian Indarto Susilo, Joni Wahyuhadi.
PY - 2021
Y1 - 2021
N2 - The use of corticosteroids in cases of brain tumors has become common to reduce brain edema. However, the use can cause adrenal insufficiency (AI) if used long-term and in large doses and with rapid withdrawal. In cases of pituitary macroadenoma that has undergone surgery, AI may also occur. AI also affects the treatment of brain tumor patients. Hence, AI is an important problem in brain tumors because almost all patients with brain tumors receive corticosteroids at some point in the course of their disease. The management is similar to another AI with focus of hydrocortisone treatment. The adjustment of hydrocortisone dosage in patients whom undergo brain surgery is similar with another major surgery, whether the adjustment for pituitary adenoma patients whom undergo excision is more complicated and careful due to the high risk and incidence of AI in these patients.
AB - The use of corticosteroids in cases of brain tumors has become common to reduce brain edema. However, the use can cause adrenal insufficiency (AI) if used long-term and in large doses and with rapid withdrawal. In cases of pituitary macroadenoma that has undergone surgery, AI may also occur. AI also affects the treatment of brain tumor patients. Hence, AI is an important problem in brain tumors because almost all patients with brain tumors receive corticosteroids at some point in the course of their disease. The management is similar to another AI with focus of hydrocortisone treatment. The adjustment of hydrocortisone dosage in patients whom undergo brain surgery is similar with another major surgery, whether the adjustment for pituitary adenoma patients whom undergo excision is more complicated and careful due to the high risk and incidence of AI in these patients.
KW - Adrenal insufficiency
KW - Brain tumor
KW - Corticosteroid
UR - http://www.scopus.com/inward/record.url?scp=85100343554&partnerID=8YFLogxK
U2 - 10.3889/oamjms.2021.5597
DO - 10.3889/oamjms.2021.5597
M3 - Article
AN - SCOPUS:85100343554
SN - 1857-5749
VL - 9
SP - 31
EP - 35
JO - Open Access Macedonian Journal of Medical Sciences
JF - Open Access Macedonian Journal of Medical Sciences
ER -