TY - JOUR
T1 - Correlation oral hairy leukoplakia and CD4+ counts in HIV/AIDS patients at Dr. soetomo hospital Surabaya, Indonesia 2014
AU - Parmadiati, Adiastuti Endah
AU - Ernawati, Diah Savitri
AU - Soebadi, Bagus
AU - Nugraha, Alexander Patera
AU - Triyono, Erwin Asta
AU - Prasetyo, Remita Adya
AU - Budi, Sulistyowati
PY - 2017
Y1 - 2017
N2 - Indonesia is a one of the countries in South East Asia with a high prevalence of HIV/AIDS cases. Oral Hairy Leukoplakia (OHL) is the one of the oral manifestations that often found in HIV/AIDS patient decreased CD4+ counts. OHL play an important role and it can be used as a clinical biomarker to determine the stage, progression, predict the onset of opportunistic diseases and a strong indicator of immunodeficiency condition. The aim of this study to investigate correlation OHL and CD4+ counts in HIV/AIDS patients at UPIPI RSUD DR. Soetomo Surabaya 2014. This study was an analytic observational study with cross-sectional and total sampling method was conductet at UPIPI RSUD Dr. Soetomo. The samples consisted of 88 HIV/AIDS patients from July-August 2014. Diagnosed of OHL based on clinical appearance, the oral cavity of research subjects examined by oral medicine specialist. CD4+ counts obtained from patient's medical record. 88 HIV/AIDS patients were examined; there were 15 patients with OHL (17,05%). OHL was found to be significantly correlated to decreased of CD4+ counts < 200 cells/mm3 (p < 0.05). Decreased of CD4+ counts affect the occurrence of OHL. OHL may be used as an alternative to CD4 count to diagnose the immunodeficiency HIV/AIDS patients.
AB - Indonesia is a one of the countries in South East Asia with a high prevalence of HIV/AIDS cases. Oral Hairy Leukoplakia (OHL) is the one of the oral manifestations that often found in HIV/AIDS patient decreased CD4+ counts. OHL play an important role and it can be used as a clinical biomarker to determine the stage, progression, predict the onset of opportunistic diseases and a strong indicator of immunodeficiency condition. The aim of this study to investigate correlation OHL and CD4+ counts in HIV/AIDS patients at UPIPI RSUD DR. Soetomo Surabaya 2014. This study was an analytic observational study with cross-sectional and total sampling method was conductet at UPIPI RSUD Dr. Soetomo. The samples consisted of 88 HIV/AIDS patients from July-August 2014. Diagnosed of OHL based on clinical appearance, the oral cavity of research subjects examined by oral medicine specialist. CD4+ counts obtained from patient's medical record. 88 HIV/AIDS patients were examined; there were 15 patients with OHL (17,05%). OHL was found to be significantly correlated to decreased of CD4+ counts < 200 cells/mm3 (p < 0.05). Decreased of CD4+ counts affect the occurrence of OHL. OHL may be used as an alternative to CD4 count to diagnose the immunodeficiency HIV/AIDS patients.
KW - CD4+
KW - Clinical biomarker
KW - HIV/AIDS
KW - Oral hairy leukoplakia
KW - Oral manifestation
UR - http://www.scopus.com/inward/record.url?scp=85018782439&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85018782439
SN - 1309-100X
VL - 10
SP - 162
EP - 165
JO - Journal of International Dental and Medical Research
JF - Journal of International Dental and Medical Research
IS - 1
ER -
