CORRELATION OF SERUM IMMUNOGLOBULIN G AND IMMUNOGLOBULIN M LEVEL WITH LENGTH OF STAY IN COVID-19 INTENSIVE CARE UNIT AFTER TREATMENT OF CONCALESCENT PLASMA

The coronavirus disease 2019 (COVID-19) pandemic has had health and economic impacts. Nearly a third of COVID-19 infections were in the 31-45 years age group (29.3%) but the highest mortality rate occurred in the elderly (17.68%). Another therapy needed to improve outcomes for critically ill COVID-19 patients is plasma therapy. This study aims to analyze the correlation of serum IgG and IgM levels with length of stay after convalescent plasma therapy in the COVID-19 ICU, Panglima Sebaya Hospital, East Kalimantan. This type of research is analytic observational with cross-sectional method. Source of data is secondary data from patient registration and medical records. Taking the number of samples using the Slovin formula, obtained 50 samples. The sampling technique used was non-probability sampling. Statistical analysis using the Pearson Correlation test if the data is normally distributed, or the Spearman Correlation Test if the data is not normally distributed. The results showed a correlation between increased serum IgG levels and length of treatment with p values = 0.202 and =-0.184. Correlation results of increasing serum IgM levels with length of treatment with p value = 0.085 and β value = 0.246. There is no correlation between the increase in serum IgG and IgM levels with the length of patient care after convalescent plasma therapy in the ICU COVID-19 Panglima Sebaya Hospital, Kab. Paser, East Kalimantan.