Correlation of chemotherapy costs with quality of life in nasopharyngeal cancer patients

Achmad Chusnu Romdhoni, Riskha Aulia, Ririn Prasetyo Utaminingtyas, Suharjono, Christopher Paul Alderman

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Background: Nasopharyngeal cancer (NPC) is the most common neck/head cancer occurring in Indonesia and is the fourth most malignant after breast cancer, cervical cancer, and lung cancer. It is known that the cost of chemotherapy may not be separated from quality of life (QoL) to reflect the success of therapy, especially in cancer patients. Thus, studies on the correlation between chemotherapy cost and the QoL in NPC patients are needed. Methods: The participants were recruited by a consecutive sampling method. All patients diagnosed with NPC using a paclitaxel-cisplatin chemotherapy regimen in August-March 2019 for first until the third chemotherapy cycle were assessed for their the chemotherapy cost and QoL before the first chemotherapy cycle and after the third cycle using the EORTC QLQ-C30 questionnaire. Chemotherapy cost and QoL were analyzed using SPSS version 20 to find out the correlation. Results: Data from 26 patients showed a notable increase in the QoL after the third chemotherapy cycle. Thus, there was a relationship between chemotherapy cost and QoL in NPC patients. The total cost of chemotherapy increased with the increase in cycles of chemotherapy. We further analyzed the correlation between QoL and the cost of chemotherapy. We found that there was a correlation between the cost and the aspects of global health status, the QoL. Conclusions: It is concluded that chemotherapy that is followed by the increase in cost in chemotherapy improves the QoL.

Original languageEnglish
Article number20190238
JournalJournal of Basic and Clinical Physiology and Pharmacology
Volume30
Issue number6
DOIs
Publication statusPublished - 2020

Keywords

  • Chemotherapy
  • Cisplatin
  • Cost
  • Nasopharyngeal cancer
  • Paclitaxel
  • QoL

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