TY - JOUR
T1 - Coronary Artery Wall Thickness and Lumen Diameter of Nicotine-Induced White Rats (Rattus norvegicus)
AU - Anisah, Nur
AU - Yunita, Maya Nurwartanti
AU - Plumeriastuti, Hani
AU - Agustono, Bodhi
AU - Rahmaniar, Reina Puspita
N1 - Publisher Copyright:
© 2023 Indian Veterinary Assocaition. All rights reserved.
PY - 2023/4
Y1 - 2023/4
N2 - Nicotine can cause hemodynamic disorders for good health. This study aimed to observe the histopathology of lumen diameter and coronary artery wall thickness in white rats exposed to nicotine. Rats were divided into five treatment groups, C (without nicotine exposure), T1,T2,T3, and T4 (nicotine concentration 0,005mg/ml; 0,05mg/ml; 0,2mg /ml, and 0.65 mg/ml). The results showed a significant difference in coronary artery wall thickness between the control and treatment groups. The diameter of the coronary artery lumen was narrowed. In conclusion, a higher concentration of nicotine can increase the thickness of the coronary artery wall and decrease the lumen diameter.
AB - Nicotine can cause hemodynamic disorders for good health. This study aimed to observe the histopathology of lumen diameter and coronary artery wall thickness in white rats exposed to nicotine. Rats were divided into five treatment groups, C (without nicotine exposure), T1,T2,T3, and T4 (nicotine concentration 0,005mg/ml; 0,05mg/ml; 0,2mg /ml, and 0.65 mg/ml). The results showed a significant difference in coronary artery wall thickness between the control and treatment groups. The diameter of the coronary artery lumen was narrowed. In conclusion, a higher concentration of nicotine can increase the thickness of the coronary artery wall and decrease the lumen diameter.
KW - Key words : coronary artery
KW - good health
KW - histopathology
KW - nicotine
KW - white rats
UR - http://www.scopus.com/inward/record.url?scp=85164592417&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85164592417
SN - 0019-6479
VL - 100
SP - 15
EP - 18
JO - Indian Veterinary Journal
JF - Indian Veterinary Journal
IS - 4
ER -