Compliance of Iron Supplementation and Determinants among Adolescent Girls: A Systematic Review

Hanna Tabita Hasianna Silitonga, Lutfi Agus Salim, Ira Nurmala, Minarni Wartiningsih

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)


Background: Iron deficiency anemia in children or women in pregnancy, is a public health problem in some countries. The World Health Organization (WHO) has called on all countries to achieve a 5% reduction in anemia in women of childbearing age, including adolescent girls, by 2025. One of the pro-grams is iron supplementation. The success depends on the adherence of adolescent girls to consume iron tablets. This systematic review aimed to find the level of compliance to iron supplementation consumption among adolescent girls and explore barriers and facilitator factors to such adherence. Methods: This article was a systematic review and conducted a multi-database search. The articles passed the PRISMA flow diagram process. The inclusion and exclusion rules decided the qualification of studies included. Of 1066 articles, we obtained 20 studies for the systematic review. Result: The lowest compliance found were 26.2% and 26.3%, and was high (>80%) in intervention studies involving supervision and monitoring and peer educator. All articles' barrier and facilitator factors were classified into four categories; personal, social, environmental, and regimen. Conclusion: Efforts to improve adolescent compliance to take iron tablets should consider all of these factors.

Original languageEnglish
Pages (from-to)37-48
Number of pages12
JournalIranian Journal of Public Health
Issue number1
Publication statusPublished - 2023


  • Adolescent
  • Compliance
  • Iron-deficiency anemia
  • Woman


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