Clinical and Radiological Factors Affecting Thoracolumbar Fractures Outcome: WFNS Spine Committee Recommendations

Francesco Costa, Salman Sharif, Abdul Hafid Bajamal, Yousuf Shaikh, Carla D. Anania, Mehmet Zileli

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)


To obtain a list of recommendations about clinical and radiological factors affecting outcome in thoracolumbar fractures with the aim of helping spine surgeons in daily practice. A systematic literature search in PubMed and Google Scholar database was done from 2010 to 2020 on the topic “thoracolumbar fracture AND radiology AND surgical outcomes” and “thoracolumbar fracture AND radiology AND surgical outcomes.” A total of 58 papers were analyzed and WFNS (World Federation of Neurosurgical Societies) Spine Committee organized 2 consensus meetings to formulate the specific recommendations the first in Peshawar in December 2019 and in a subsequent virtual meeting in June 2020 to reach an agreement. Both meetings utilized the Delphi method to analyze preliminary literature review statements based on the current evidence levels to generate recommendations through a comprehensive voting session. Eight statements were presented and reached the consensus about this topic. A variety of clinical factors is known to influence outcome of patients with thoracolumbar fractures. Some of these are well-known established factors such as blood pressure augmentation and patient age, while some are not well studied. Overall, the quality of evidence is low and we need more randomized controlled studies to validate our results. Similarly, radiological factors that can predict outcome are well stated and there is a high accordance worldwide. In reverse, still under debate is the application to choose which surgical treatment is advisable based on them.

Original languageEnglish
Pages (from-to)693-703
Number of pages11
Issue number4
Publication statusPublished - Dec 2021


  • Clinical factors
  • Outcome
  • Radiological factors
  • Thoracolumbar fractures
  • WFNS recommendations


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