Characterization of Tilapia collagen-loaded chitosan nanofibers synthesized by electrospinning method for wound dressing

C. A.M. Rani, A. Safira, M. Suryadiningrat, F. Fikri, D. K. Wardhana, M. T.E. Purnama

Research output: Contribution to journalConference articlepeer-review

1 Citation (Scopus)

Abstract

Burns are traumatic injuries that require intensive therapy. Tilapia skin is known to contain high collagen properties and was developed for wound dressing. This study aimed to investigate the characterization of Tilapia collagen-loaded chitosan nanofibers synthesized by electrospinning for wound dressing. This study evaluated three group materials, i.e. (G1) chitosan, (G2) Tilapia collagen, and (G3) Tilapia collagen-loaded chitosan. The electrospun method was performed by alloy the chitosan nanofibers containing 8% w/v Tilapia collagen. The mix solution was characterized using scanning electron microscopy (SEM), Fourier- transform infrared (FTIR) spectroscopy, pH level, swelling test, water capacity test, and cytotoxicity test. As result, Tilapia collagen-loaded chitosan showed the better swelling test, water capacity test, cytotoxicity test, and FTIR evaluation compared to the collagen or chitosan group. However, all group materials showed similarities in pH level and SEM evaluation. In conclusion, Tilapia collagen-loaded chitosan nanofibers could be considered as a wound dressing based on positive results during characterization.

Original languageEnglish
Article number012034
JournalIOP Conference Series: Earth and Environmental Science
Volume1036
Issue number1
DOIs
Publication statusPublished - 2022
Event4th International Conference on Fisheries and Marine Sciences, INCOFIMS 2021 - Surabaya, Virtual, Indonesia
Duration: 29 Sep 2021 → …

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