TY - JOUR
T1 - Characterization of Bovine Sponge Amnion (BSA) by a Novel Process for Dental Treatment
AU - Octarina,
AU - Munadziroh, Elly
AU - Razak, Fathilah Abdul
AU - Abbas, Basril
AU - Soekartono, Helal
AU - Agustantina, Titien Hary
AU - Surboyo, Meircurius Dwi Condro
N1 - Publisher Copyright:
© 2022. Journal of International Dental and Medical Research. All Rights Reserved.
PY - 2022
Y1 - 2022
N2 - One of dental treatments in dentistry is tooth extraction. This treatment will cause injury after extraction and biomaterial is needed to accelerate wound healing. Bovine amniotic membrane is a biomaterial with collagen content that can accelerate wound healing. However, in the process of application, the membrane will tear easily and is difficult to apply. The purpose of this study was to fabricate the bovine amniotic membrane into bovine sponge amnion (BSA) and characterize it. BSA was derived from bovine amniotic membrane with the addition of gelatin which then underwent freeze-drying process and lyophilization. BSA was then characterized using Fourier Transform Infrared Spectroscopy (FTIR), scanning electron microscopy (SEM), and swelling test. The result of characterization using FTIR indicated that amide A, amide B, amide I, amide II, and triple helix of collagen groups were shown in the FTIR graphs. The surface characterization using SEM showed a mean porosity size of 304.866 μm with a porosity proportion of 64%. The swelling analysis showed the proportion of swelling was 1320 times. The BSA has an ideal pore size, functional group and swelling ability for biomaterial candidate in dentistry.
AB - One of dental treatments in dentistry is tooth extraction. This treatment will cause injury after extraction and biomaterial is needed to accelerate wound healing. Bovine amniotic membrane is a biomaterial with collagen content that can accelerate wound healing. However, in the process of application, the membrane will tear easily and is difficult to apply. The purpose of this study was to fabricate the bovine amniotic membrane into bovine sponge amnion (BSA) and characterize it. BSA was derived from bovine amniotic membrane with the addition of gelatin which then underwent freeze-drying process and lyophilization. BSA was then characterized using Fourier Transform Infrared Spectroscopy (FTIR), scanning electron microscopy (SEM), and swelling test. The result of characterization using FTIR indicated that amide A, amide B, amide I, amide II, and triple helix of collagen groups were shown in the FTIR graphs. The surface characterization using SEM showed a mean porosity size of 304.866 μm with a porosity proportion of 64%. The swelling analysis showed the proportion of swelling was 1320 times. The BSA has an ideal pore size, functional group and swelling ability for biomaterial candidate in dentistry.
KW - Biomaterials
KW - Biomedical
KW - Bovine amniotic membrane
KW - Bovine sponge amnion
KW - Human & health
UR - http://www.scopus.com/inward/record.url?scp=85133778611&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85133778611
SN - 1309-100X
VL - 15
SP - 479
EP - 484
JO - Journal of International Dental and Medical Research
JF - Journal of International Dental and Medical Research
IS - 2
ER -