TY - GEN
T1 - Characteristic of bovine hydroxyapatite-gelatin-chitosan scaffolds as biomaterial candidate for bone tissue engineering
AU - Kartikasari, Nadia
AU - Yuliati, Anita
AU - Listiana, Indah
AU - Setijanto, Darmawan
AU - Suardita, Ketut
AU - Ariani, Maretaningtyas Dwi
AU - Sosiawan, Agung
N1 - Publisher Copyright:
© 2016 IEEE.
PY - 2016
Y1 - 2016
N2 - Bone defect is still a major problem in dentistry. Solving this problem, tissue engineering becomes one of the promising methods for bone regeneration. One of main component of tissue engineering is scaffolds. Hydroxyapatite (HA) and natural polymer are widely used for scaffolds in bone tissue engineering due to similarity to the natural bone. In this study, the author prepared the scaffolds from bovine hydroxyapatite (BHA), gelatin (GEL) and chitosan (K). The prepared scaffolds were analyzed by using FTIR and SEM-EDX. In addition, its swelling and degradation rate are also included in this analysis. The results are (1) FTIR reveals the compositions of the scaffolds, and it consists of BHA, GEL, and K; (2) SEM-EDX reveals the elements of the scaffolds, and it consists of carbon (C), oxygen (O), natrium (Na), magnesium (Mg), phosphor (P), and calcium (Ca); (3) the scaffolds' swelling rate is good due to its hydrophilic composition; (4) and the degradation rate is low within three days. The four results show that the BHA-GEL-K scaffolds could be one of biomaterial candidate for bone tissue engineering.
AB - Bone defect is still a major problem in dentistry. Solving this problem, tissue engineering becomes one of the promising methods for bone regeneration. One of main component of tissue engineering is scaffolds. Hydroxyapatite (HA) and natural polymer are widely used for scaffolds in bone tissue engineering due to similarity to the natural bone. In this study, the author prepared the scaffolds from bovine hydroxyapatite (BHA), gelatin (GEL) and chitosan (K). The prepared scaffolds were analyzed by using FTIR and SEM-EDX. In addition, its swelling and degradation rate are also included in this analysis. The results are (1) FTIR reveals the compositions of the scaffolds, and it consists of BHA, GEL, and K; (2) SEM-EDX reveals the elements of the scaffolds, and it consists of carbon (C), oxygen (O), natrium (Na), magnesium (Mg), phosphor (P), and calcium (Ca); (3) the scaffolds' swelling rate is good due to its hydrophilic composition; (4) and the degradation rate is low within three days. The four results show that the BHA-GEL-K scaffolds could be one of biomaterial candidate for bone tissue engineering.
KW - BHA-GEL-K
KW - FTIR
KW - SEM-EDX
KW - degradation
KW - scaffolds
KW - swelling
UR - http://www.scopus.com/inward/record.url?scp=85015686814&partnerID=8YFLogxK
U2 - 10.1109/IECBES.2016.7843524
DO - 10.1109/IECBES.2016.7843524
M3 - Conference contribution
AN - SCOPUS:85015686814
T3 - IECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences
SP - 623
EP - 626
BT - IECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2016 IEEE-EMBS Conference on Biomedical Engineering and Sciences, IECBES 2016
Y2 - 4 December 2016 through 8 December 2016
ER -