Characteristic of bovine hydroxyapatite-gelatin-chitosan scaffolds as biomaterial candidate for bone tissue engineering

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8 Citations (Scopus)

Abstract

Bone defect is still a major problem in dentistry. Solving this problem, tissue engineering becomes one of the promising methods for bone regeneration. One of main component of tissue engineering is scaffolds. Hydroxyapatite (HA) and natural polymer are widely used for scaffolds in bone tissue engineering due to similarity to the natural bone. In this study, the author prepared the scaffolds from bovine hydroxyapatite (BHA), gelatin (GEL) and chitosan (K). The prepared scaffolds were analyzed by using FTIR and SEM-EDX. In addition, its swelling and degradation rate are also included in this analysis. The results are (1) FTIR reveals the compositions of the scaffolds, and it consists of BHA, GEL, and K; (2) SEM-EDX reveals the elements of the scaffolds, and it consists of carbon (C), oxygen (O), natrium (Na), magnesium (Mg), phosphor (P), and calcium (Ca); (3) the scaffolds' swelling rate is good due to its hydrophilic composition; (4) and the degradation rate is low within three days. The four results show that the BHA-GEL-K scaffolds could be one of biomaterial candidate for bone tissue engineering.

Original languageEnglish
Title of host publicationIECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages623-626
Number of pages4
ISBN (Electronic)9781467377911
DOIs
Publication statusPublished - 2016
Event2016 IEEE-EMBS Conference on Biomedical Engineering and Sciences, IECBES 2016 - Kuala Lumpur, Malaysia
Duration: 4 Dec 20168 Dec 2016

Publication series

NameIECBES 2016 - IEEE-EMBS Conference on Biomedical Engineering and Sciences

Conference

Conference2016 IEEE-EMBS Conference on Biomedical Engineering and Sciences, IECBES 2016
Country/TerritoryMalaysia
CityKuala Lumpur
Period4/12/168/12/16

Keywords

  • BHA-GEL-K
  • FTIR
  • SEM-EDX
  • degradation
  • scaffolds
  • swelling

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