Changes of interleukin-6 (Il-6) and immunoglobulin g (igg) in respiratory excercise

Didik Agus Santoso, F. M. Judajana, Elyana Asnar

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Background: Skeletal muscle contraction in exercise will synthesize and release Interleukin-6 (IL-6) into the systemic circulation. IL-6 is a pleiotropic, proinflammatory and anti-inflammatory cytokine. IL-6 in exercise can modulate the immune response and metabolism in the liver, adipose tissue, Hypothalamus-hypophyse-adrenal (HPA). Objectives: To analyze and prove changes in levels of Interleukin-6 (IL-6) and Immunoglobulin G (IgG) in respiratory art sports of a exercise club. Methods: Thirty-four members of the breathing arts sport who met the inclusion criteria, male sex, adult age (≥21 years), willing to participate were enrolled in this study. Examination of IL-6 and igG levels were performed by using Elisa method. The kit for IL-6 used Human IL-6 Immunoassay and IgG level used Total Human IgG Assay Results: The t-test results obtained p = 0.027 (p <0.05), there was a change between IL-6 pre-test and IL-6 post-test of breathing exercise for three weeks. The t-test results obtained p = 0.000 (p <0.05) there was a change between IgG level of pre-test and IgG post-test of breathing arts sports treatment, this change increased significantly. Conclusion: There was a change in levels of IL-6 and IgG in the breathing excercise.

Original languageEnglish
Pages (from-to)1501-1506
Number of pages6
JournalIndian Journal of Forensic Medicine and Toxicology
Issue number2
Publication statusPublished - 1 Apr 2020


  • Adipose tissue
  • Breathing exercise
  • IgG
  • IL-6


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