TY - JOUR
T1 - Challenge of Ziehl-Neelsen stain for Basidiobolomycosis diagnosis in Indonesia
T2 - A unique case report
AU - Octora, Metta
AU - Kawilarang, Arthur Pohan
AU - Endraswari, Pepy Dwi
N1 - Publisher Copyright:
© 2022 The Authors
PY - 2022/2
Y1 - 2022/2
N2 - Background: Basidiobolomycosis is a rare fungal infection in Indonesia, so alternative investigations are needed to make a diagnosis. Case presentation: A 24-year-old male patient, Javanese, presented with Basidiobolomycosis. The patient had a lump on the right arm and face 2 years ago, and the tumor progressively grew up and extended to the right upper arm, neck, and face since 1 month ago. This paper discussed the challenge of Ziehl-Neelsen (ZN) stain as a diagnostic tool for Basidiobolomycosis that is a rare case in the world, especially in Indonesia. Discussion: Acid-fast stain has never been used to diagnose fungal cases in general, but it could describe the hyphae and Splendore-Hoeppli very clearly compared to the standard hematoxylin and eosin (HE) stains. Conclusion: ZN can be used as an alternative diagnosis of Basidiobolomycosis in a low-resource setting.
AB - Background: Basidiobolomycosis is a rare fungal infection in Indonesia, so alternative investigations are needed to make a diagnosis. Case presentation: A 24-year-old male patient, Javanese, presented with Basidiobolomycosis. The patient had a lump on the right arm and face 2 years ago, and the tumor progressively grew up and extended to the right upper arm, neck, and face since 1 month ago. This paper discussed the challenge of Ziehl-Neelsen (ZN) stain as a diagnostic tool for Basidiobolomycosis that is a rare case in the world, especially in Indonesia. Discussion: Acid-fast stain has never been used to diagnose fungal cases in general, but it could describe the hyphae and Splendore-Hoeppli very clearly compared to the standard hematoxylin and eosin (HE) stains. Conclusion: ZN can be used as an alternative diagnosis of Basidiobolomycosis in a low-resource setting.
KW - Acid-fast stain
KW - Basidiobolomycosis
KW - Splendore Hoeppli phenomenon
UR - http://www.scopus.com/inward/record.url?scp=85123692637&partnerID=8YFLogxK
U2 - 10.1016/j.amsu.2022.103278
DO - 10.1016/j.amsu.2022.103278
M3 - Article
AN - SCOPUS:85123692637
SN - 2049-0801
VL - 74
JO - Annals of Medicine and Surgery
JF - Annals of Medicine and Surgery
M1 - 103278
ER -