TY - JOUR
T1 - Case report
T2 - Reconstructive cholecystectomy and conservative treatment autoimmune hemolytic anemia (aiha) in conjunction with cholelithiasis
AU - Cendikia, Muhammad Nuriman
AU - Kholili, Ulfa
N1 - Publisher Copyright:
© 2025 by SPC (Sami Publishing Company).
PY - 2025/2
Y1 - 2025/2
N2 - Autoimmune hemolytic anemia (AIHA) is a rare and heterogeneous disease that affects 1 to 3/100000 patients in a year. Therefore, it is necessary to analyze therapy modifications by advantages and side effects. The main cause of autoimmune hemolytic anemia (AIHA) is an elevated immune response leading to the destruction of one's own red blood cells, known as lysis. Gallstones are non-living clumps that can form either in the bile ducts (choledocholithiasis) or in the gallbladder (cholelithiasis). This case study examines patients suffering from cholelithiasis and AIHA in a 71 year old female patient from Airlangga University Hospital, Surabaya. The diagnosis, based on the patient's medical history, physical examination, and labolatory test results, forms the basis for the therapy's guiding principles. Patients with very mild or no symptoms can receive conservative therapy, which is a non-surgical therapeutic option. Surgical treatment may be advantageous for individuals with symptomatic cholelithiasis who often or severely suffer symptoms due to the possibility of complications. Three criteria are taken into consideration when evaluating the approach to be used: severe symptoms, complications, and other conditions that raise the chance of complication. Accordingly, patients should have access to elective cholecystectomy. Given the potential challenges associated with cholelithiasis, we present a case report of a patient with AIHA who also has this condition.
AB - Autoimmune hemolytic anemia (AIHA) is a rare and heterogeneous disease that affects 1 to 3/100000 patients in a year. Therefore, it is necessary to analyze therapy modifications by advantages and side effects. The main cause of autoimmune hemolytic anemia (AIHA) is an elevated immune response leading to the destruction of one's own red blood cells, known as lysis. Gallstones are non-living clumps that can form either in the bile ducts (choledocholithiasis) or in the gallbladder (cholelithiasis). This case study examines patients suffering from cholelithiasis and AIHA in a 71 year old female patient from Airlangga University Hospital, Surabaya. The diagnosis, based on the patient's medical history, physical examination, and labolatory test results, forms the basis for the therapy's guiding principles. Patients with very mild or no symptoms can receive conservative therapy, which is a non-surgical therapeutic option. Surgical treatment may be advantageous for individuals with symptomatic cholelithiasis who often or severely suffer symptoms due to the possibility of complications. Three criteria are taken into consideration when evaluating the approach to be used: severe symptoms, complications, and other conditions that raise the chance of complication. Accordingly, patients should have access to elective cholecystectomy. Given the potential challenges associated with cholelithiasis, we present a case report of a patient with AIHA who also has this condition.
KW - AIHA
KW - Cholecystectomy
KW - cholelithiasis
UR - http://www.scopus.com/inward/record.url?scp=85202520225&partnerID=8YFLogxK
U2 - 10.48309/jmpcr.2025.457368.1240
DO - 10.48309/jmpcr.2025.457368.1240
M3 - Article
AN - SCOPUS:85202520225
SN - 2981-0221
VL - 7
SP - 207
EP - 214
JO - Journal of Medicinal and Pharmaceutical Chemistry Research
JF - Journal of Medicinal and Pharmaceutical Chemistry Research
IS - 2
ER -