TY - JOUR
T1 - Carbon nanomaterials as electrochemical sensors for theophylline
T2 - a review
AU - Gabrielle Sutanto, Laurencia
AU - Sabilla, Syarifa
AU - Wardhana, Brasstira Yuva
AU - Ramadani, Anggi
AU - Sari, Anis Puspita
AU - Anjani, Qonita Kurnia
AU - Basirun, Wan Jeffrey
AU - Amrillah, Tahta
AU - Amalina, Ilma
AU - Jiwanti, Prastika Krisma
N1 - Publisher Copyright:
© 2024 The Royal Society of Chemistry.
PY - 2024/9/11
Y1 - 2024/9/11
N2 - Theophylline (TP) is a methylxanthine derivative, which serves as a valuable compound in treating respiratory disorders and acts as a bronchodilator agent. However, TP has a limited therapeutic range (20-100 μmol L−1), demanding precise monitoring to prevent potential drug toxicity even with slight level fluctuations during treatment. Thus, to overcome this limitation, electrochemical methods have been extensively used due to their efficacy in achieving sensitivity, selectivity, and accuracy. In the context of electrochemical sensors, nanocarbon-based materials have gained widespread recognition for their extensive applications. Therefore, this review aims to explore the latest advancements in carbon-based electrodes particularly used for the precise determination of TP through electrochemical methods. The results are expected to provide insights into the profound significance of the methods in enhancing the accuracy and sensitivity for the detection of TP.
AB - Theophylline (TP) is a methylxanthine derivative, which serves as a valuable compound in treating respiratory disorders and acts as a bronchodilator agent. However, TP has a limited therapeutic range (20-100 μmol L−1), demanding precise monitoring to prevent potential drug toxicity even with slight level fluctuations during treatment. Thus, to overcome this limitation, electrochemical methods have been extensively used due to their efficacy in achieving sensitivity, selectivity, and accuracy. In the context of electrochemical sensors, nanocarbon-based materials have gained widespread recognition for their extensive applications. Therefore, this review aims to explore the latest advancements in carbon-based electrodes particularly used for the precise determination of TP through electrochemical methods. The results are expected to provide insights into the profound significance of the methods in enhancing the accuracy and sensitivity for the detection of TP.
UR - http://www.scopus.com/inward/record.url?scp=85203861991&partnerID=8YFLogxK
U2 - 10.1039/d4ra03585b
DO - 10.1039/d4ra03585b
M3 - Review article
AN - SCOPUS:85203861991
SN - 2046-2069
VL - 14
SP - 28927
EP - 28942
JO - RSC Advances
JF - RSC Advances
IS - 39
ER -