TY - JOUR
T1 - Calotetrapterins A-C, three new pyranoxanthones and their cytotoxicity from the stem bark of Calophyllum tetrapterum Miq
AU - Tanjung, Mulyadi
AU - Tjahjandarie, Tjitjik Srie
AU - Saputri, Ratih Dewi
AU - Kurnia, Baharrani Dwi
AU - Rachman, Muhammad Faisal
AU - Syah, Yana Maolana
N1 - Publisher Copyright:
© 2019 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2021
Y1 - 2021
N2 - Three new pyranoxanthones, calotetrapterins A-C (1-3) were isolated from the stem bark of Calophyllum tetrapterum Miq along with three known xanthones, α-mangostin (4), garciniafuran (5), and pyranojacareubin (6). All structures were elucidated based on their IR, UV, HRESIMS, 1 D (1H, 13C) and 2 D (HMBC, HMQC) NMR spectral data. Compounds 1-6 were tested to P-388 cells for cytotoxic activity, compound 2 exhibited high activity with IC50 value 1.0 μM.
AB - Three new pyranoxanthones, calotetrapterins A-C (1-3) were isolated from the stem bark of Calophyllum tetrapterum Miq along with three known xanthones, α-mangostin (4), garciniafuran (5), and pyranojacareubin (6). All structures were elucidated based on their IR, UV, HRESIMS, 1 D (1H, 13C) and 2 D (HMBC, HMQC) NMR spectral data. Compounds 1-6 were tested to P-388 cells for cytotoxic activity, compound 2 exhibited high activity with IC50 value 1.0 μM.
KW - Calophyllum tetrapterum
KW - Calotetrapterins A-C
KW - P-388 cell
KW - pyranoxanthone
UR - https://www.scopus.com/pages/publications/85069055203
U2 - 10.1080/14786419.2019.1634714
DO - 10.1080/14786419.2019.1634714
M3 - Article
C2 - 31305138
AN - SCOPUS:85069055203
SN - 1478-6419
VL - 35
SP - 407
EP - 412
JO - Natural Product Research
JF - Natural Product Research
IS - 3
ER -