TY - JOUR
T1 - Bovine Pericardium-Chitosan As A Biomaterial Prospect for Substitute and Accelerate Tissue Healing of Dural Defect
T2 - A Review
AU - Fauzi, Asra Al
AU - Suroto, Heri
AU - Widiyanti, Prihartini
AU - Suroto, Nur Setiawan
AU - Fauza, Joandre
AU - Hidayat Thamrin, Ahmad Muslim
AU - Bella, Fitria Renata
N1 - Publisher Copyright:
© 2021 UPM Press. All rights reserved.
PY - 2021/9
Y1 - 2021/9
N2 - In the field of neurosurgery, duraplasty is commonly performed after intradural surgery which requires excision of the dura mater and/ or in the case of head injury. Over the past century, several biomaterials have been investigated as a dural substitute for duraplasty. Bovine pericardium (xenograft) has been widely studied in clinical trials and is commercialized as a graft in cardiac surgery, as well as a dural substitute. Bovine pericardium as a dural substitute is elastic, suturable, and provides watertight capabilities. Another biomaterial that also has many biologic advantages is chitosan. Chitosan has been widely known as a good agent for wound healing, because of its hemostatic properties and its ability in reducing inflammation. The availability and benefits of both materials make it an interesting subject for further research. This review aims to provides knowledge about the potential bovine pericardium in combination with chitosan as a dural substitute, which not only provides watertight properties, but also accelerates tissue healing in dural defects.
AB - In the field of neurosurgery, duraplasty is commonly performed after intradural surgery which requires excision of the dura mater and/ or in the case of head injury. Over the past century, several biomaterials have been investigated as a dural substitute for duraplasty. Bovine pericardium (xenograft) has been widely studied in clinical trials and is commercialized as a graft in cardiac surgery, as well as a dural substitute. Bovine pericardium as a dural substitute is elastic, suturable, and provides watertight capabilities. Another biomaterial that also has many biologic advantages is chitosan. Chitosan has been widely known as a good agent for wound healing, because of its hemostatic properties and its ability in reducing inflammation. The availability and benefits of both materials make it an interesting subject for further research. This review aims to provides knowledge about the potential bovine pericardium in combination with chitosan as a dural substitute, which not only provides watertight properties, but also accelerates tissue healing in dural defects.
KW - Bovine Pericardium
KW - Chitosan
KW - Dural Substitute
KW - Tissue Healing
KW - Xenograft
UR - http://www.scopus.com/inward/record.url?scp=85117119126&partnerID=8YFLogxK
M3 - Review article
AN - SCOPUS:85117119126
SN - 1675-8544
VL - 17
SP - 102
EP - 109
JO - Malaysian Journal of Medicine and Health Sciences
JF - Malaysian Journal of Medicine and Health Sciences
ER -