Bioviability of Beta-Tricalcium Phosphate Nanoencapsulation from Synthesis of Anadara granosa Shells on Fibroblast Cell Line BHK-21 Cell Culture

Aprilia, Sri Kunarti, Theresia Indah Budhy, Rima Parwati Sari

Research output: Contribution to journalArticlepeer-review

Abstract

The purpose of this research is to measure the toxicity of beta-tricalcium phosphate (β-TCP) nanoencapsulation resulting from 18 hours of hydrothermal process on Anadara granosa (A. granosa) shell and 3 hours of sintering. The encapsulation process was carried out to reduce the side and toxic effect, as well as to inhibit the speed of calcium solubility, which can prevent the tunnel effects. The result of cell viability data that analysed using the one-way ANOVA statistical test showed there was no significant difference between the A. granosa shell encapsulation processes with treatment groups of 1, 2, 3, 4, 5, and 6 hours. The highest viability occurred in treatment group 2, with the A. granosa shell encapsulation stirred process of 2 hours. Therefore, the A. granosa clam shell nanoencapsulation was proved to be non-toxic and can be used in dentistry therapy.

Original languageEnglish
Pages (from-to)7-12
Number of pages6
JournalInternational Journal of Integrated Engineering
Volume14
Issue number2
DOIs
Publication statusPublished - 2022

Keywords

  • Anadara granosa
  • Blood shells
  • Cell culture
  • Cytotoxicity
  • Encapsulation
  • Fibroblast
  • Synthesis

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