Biomass as Whitening Agents Derived from Plants

Rico Ramadhan, Rizki Maharani, Asshaima Paramita Devi, Husnul Warnida, Widya Fatriasari

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)

Abstract

Hyperpigmentation is a prevalent skin condition characterized by darkened patches or spots on the skin. Melanin, which is a pigment responsible for skin, hair, and eye coloration, can accumulate or be overproduced, leading to aesthetic concerns and potential health issues associated with hyperpigmentation. Skin lightening refers to using natural or synthetic products to reduce melanin levels and achieve a more even skin tone. While traditional depigmenting agents such as hydroquinone, corticosteroids, and kojic acid are effective, they raise safety concerns with prolonged use, including ochronosis, atrophy, carcinogenesis, and other side effects. Exploring the benefts of natural and botanical extracts offers opportunities for developing new products to address pigmentation issues. Active compounds derived from plants, such as arbutin, aloesin, gentisic acid, favonoids, hesperidin, licorice, niacinamide, yeast derivatives, and polyphenols, have been found to inhibit melanin production without harming melanocytes through various mechanisms. This chapter provides an overview of the current trends in utilizing plant extracts as topical treatments for hyperpigmentation disorders, emphasizing signifcant natural extracts and secondary metabolites, along with in vitro screening results and relevant clinical trial fndings supporting their effcacy.

Original languageEnglish
Title of host publicationBiomass-Based Cosmetics
Subtitle of host publicationResearch Trends and Future Outlook
PublisherSpringer Nature
Pages383-431
Number of pages49
ISBN (Electronic)9789819719082
ISBN (Print)9789819719075
DOIs
Publication statusPublished - 1 Jan 2024

Keywords

  • Biomass
  • Secondary metabolites
  • Tropical medicinal plants
  • Whitening agents

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