TY - GEN
T1 - Biological evaluation of PCL-AgNPs biocomposites as guided tissue regeneration membranes
AU - Widiyanti, Prihartini
AU - Lazuardi, Mohammad Bagus
N1 - Publisher Copyright:
© 2023 Author(s).
PY - 2023/5/25
Y1 - 2023/5/25
N2 - More than half of the world's population still experiences dental and mouth disease which causes disruption to the quality of human life. The number of untreated dental and oral diseases increased by 40% from 1990 to 2015 which reached 3.5 billion people and periodontal disease in severe conditions reached 573 million. One of the cases of periodontal abnormalities is the Guided tissue regeneration (GTR) method. In this study the formation of GTR membranes derived from biocomposite PCL-AgNPs using the electrospinning method. The results obtained through FTIR characterization, degradation, antibacterial, and cytotoxicity that the addition of AgNPs did not show changes in functional groups. All biocomposite GTR membrane PCL-AgNPs samples showed that AgNPs only physically bonded to PCL. Degradation characterization shows that the addition of AgNPs causes the rate of degradation to increase with increasing number of AgNPs. The addition of AgNPs also shows the ability of membranes to inhibit bacteria and viability decreases with increasing number of AgNPs.
AB - More than half of the world's population still experiences dental and mouth disease which causes disruption to the quality of human life. The number of untreated dental and oral diseases increased by 40% from 1990 to 2015 which reached 3.5 billion people and periodontal disease in severe conditions reached 573 million. One of the cases of periodontal abnormalities is the Guided tissue regeneration (GTR) method. In this study the formation of GTR membranes derived from biocomposite PCL-AgNPs using the electrospinning method. The results obtained through FTIR characterization, degradation, antibacterial, and cytotoxicity that the addition of AgNPs did not show changes in functional groups. All biocomposite GTR membrane PCL-AgNPs samples showed that AgNPs only physically bonded to PCL. Degradation characterization shows that the addition of AgNPs causes the rate of degradation to increase with increasing number of AgNPs. The addition of AgNPs also shows the ability of membranes to inhibit bacteria and viability decreases with increasing number of AgNPs.
UR - http://www.scopus.com/inward/record.url?scp=85161453769&partnerID=8YFLogxK
U2 - 10.1063/5.0136920
DO - 10.1063/5.0136920
M3 - Conference contribution
AN - SCOPUS:85161453769
T3 - AIP Conference Proceedings
BT - 3rd International Seminar on Science and Technology, ISSTEC 2021
A2 - Sahroni, Imam
A2 - Musawwa, Muhammad Miqdam
A2 - Fauzan, Achmad
A2 - Werdyani, Sista
A2 - Zain, Zainiharyati Mohd
A2 - Fatimah, Is
A2 - Riyanto, null
PB - American Institute of Physics Inc.
T2 - 3rd International Seminar on Science and Technology: Science, Technology and Data Analysis for Sustainable Future, ISSTEC 2021
Y2 - 30 November 2021
ER -
