TY - JOUR
T1 - Attitudes of indonesian medical doctors and medical students toward genome editing
AU - Izzah, Safira Nur
AU - Setyanto, Dimas
AU - Hasanatuludhhiyah, Nurina
AU - Indiastuti, Danti Nur
AU - Nasution, Zamal
AU - D’Arqom, Annette
N1 - Funding Information:
This study was funded by RKAT Faculty of Medicine Universitas Airlangga as Rector?s Decree No. 346/UN3/2020.
Funding Information:
This study was funded by RKA T Faculty of Medicine Universitas Airlangga as Rector's Decree No. 346/UN3/2020.
Publisher Copyright:
© 2021 Izzah et al. This work is published and licensed by Dove Medical Press Limited.
PY - 2021
Y1 - 2021
N2 - Purpose: This study aimed to measure the attitudes of Indonesian medical doctors and students toward new technology in genome editing. Materials and Methods: Online questionnaires regarding attitudes toward genome editing on health and non-health conditions, both in somatic cells and embryo, were distributed through researcher networks, email and social media specific to medical doctors and students. The data of 1055 valid questionnaires were processed; descriptive and association analyses between sociodemographic factors and attitudes toward genome editing were performed. Email in-depth interview was performed to explore the respondents’ answers. Results: The results showed that Indonesian medical doctors’ and students’ knowledge of genome editing was limited and correlated with gender, place of residence, religion, education, marital status, childbearing and experience abroad. More than half of respondents supported genome editing for the treatment of fatal and debilitating diseases both in somatic cells and embryos, implying their consent to edited gene inheritance. However, this approval decreased when applied to non-health-related aspects, such as physical appearance, intelligence and strength. Factors affecting their attitudes toward genome editing included their status as medical doctors or students, gender, age, education, religion, economic status and place of residence. Conclusion: Increasing knowledge and awareness of Indonesian medical doctors and students regarding genome editing is important. Even though its application in health-related matter was supported by a majority of the respondents, discussion from ethical and religious perspectives is necessary to ensure the acceptance.
AB - Purpose: This study aimed to measure the attitudes of Indonesian medical doctors and students toward new technology in genome editing. Materials and Methods: Online questionnaires regarding attitudes toward genome editing on health and non-health conditions, both in somatic cells and embryo, were distributed through researcher networks, email and social media specific to medical doctors and students. The data of 1055 valid questionnaires were processed; descriptive and association analyses between sociodemographic factors and attitudes toward genome editing were performed. Email in-depth interview was performed to explore the respondents’ answers. Results: The results showed that Indonesian medical doctors’ and students’ knowledge of genome editing was limited and correlated with gender, place of residence, religion, education, marital status, childbearing and experience abroad. More than half of respondents supported genome editing for the treatment of fatal and debilitating diseases both in somatic cells and embryos, implying their consent to edited gene inheritance. However, this approval decreased when applied to non-health-related aspects, such as physical appearance, intelligence and strength. Factors affecting their attitudes toward genome editing included their status as medical doctors or students, gender, age, education, religion, economic status and place of residence. Conclusion: Increasing knowledge and awareness of Indonesian medical doctors and students regarding genome editing is important. Even though its application in health-related matter was supported by a majority of the respondents, discussion from ethical and religious perspectives is necessary to ensure the acceptance.
KW - CRISPR/Cas
KW - Developing country
KW - Good health and well-being
UR - http://www.scopus.com/inward/record.url?scp=85105644215&partnerID=8YFLogxK
U2 - 10.2147/JMDH.S303881
DO - 10.2147/JMDH.S303881
M3 - Article
AN - SCOPUS:85105644215
SN - 1178-2390
VL - 14
SP - 1017
EP - 1027
JO - Journal of Multidisciplinary Healthcare
JF - Journal of Multidisciplinary Healthcare
ER -