TY - JOUR
T1 - Association Between Cadmium Exposure and Kidney Disorder Among Workers in the Battery Industry
AU - Choirunnisa’, Aulia
AU - Adriyani, Retno
AU - Aanisah, Yusrina Nurul
AU - Ibrahim, Ilyas
AU - Aziz, Mohd Yusmaidie
N1 - Publisher Copyright:
© 2023 IJOSH All right reserved.
PY - 2023/8/3
Y1 - 2023/8/3
N2 - Introduction: Workers in the battery industry are at risk of being exposed to cadmium (Cd), which can cause various health problems, including kidney disorders. This study aims to investigate the association between biomarkers of Cd exposure and effect with kidney disorders among workers in the battery industry. Methods: A systematic review approach was used in this study, employing relevant keywords and inclusion criteria to search electronic databases, such as Google scholar, PubMed, Science Direct, and Research Gate. The selected articles included research articles published between 2010 and 2020, with cross-sectional, cohort, and case-control study designs. To ensure the quality of the articles reviewed, the Critical Appraisal Skill Programme (CASP) was used. Results: The CASP tools facilitated the exploration of trustworthy and relevant articles for the literature review. Previous studies revealed that individuals of various ages, ranging from teenagers to adults aged 12-60, both males and females, are commonly employed in the battery industry. Cadmium was detected in the hair, urine, and blood samples of these workers. Previous studies also identified kidney disorders among these workers by analyzing biomarkers such as creatinine, retinol-binding protein, blood urea nitrogen, and hemoglobin, which were all found to be above the normal range. Furthermore, increased Cd levels in the blood of workers caused glomerular disorder and tubular dysfunction, eventually resulting in kidney function disorders. Conclusion: Cd levels in the bodies of workers in the battery industry serves as a reliable biomarker of Cd exposure, and are closely related to the number of effect biomarkers that can contribute to kidney disorders. This study emphasizes the importance of monitoring Cd exposure levels among workers in the battery industry.
AB - Introduction: Workers in the battery industry are at risk of being exposed to cadmium (Cd), which can cause various health problems, including kidney disorders. This study aims to investigate the association between biomarkers of Cd exposure and effect with kidney disorders among workers in the battery industry. Methods: A systematic review approach was used in this study, employing relevant keywords and inclusion criteria to search electronic databases, such as Google scholar, PubMed, Science Direct, and Research Gate. The selected articles included research articles published between 2010 and 2020, with cross-sectional, cohort, and case-control study designs. To ensure the quality of the articles reviewed, the Critical Appraisal Skill Programme (CASP) was used. Results: The CASP tools facilitated the exploration of trustworthy and relevant articles for the literature review. Previous studies revealed that individuals of various ages, ranging from teenagers to adults aged 12-60, both males and females, are commonly employed in the battery industry. Cadmium was detected in the hair, urine, and blood samples of these workers. Previous studies also identified kidney disorders among these workers by analyzing biomarkers such as creatinine, retinol-binding protein, blood urea nitrogen, and hemoglobin, which were all found to be above the normal range. Furthermore, increased Cd levels in the blood of workers caused glomerular disorder and tubular dysfunction, eventually resulting in kidney function disorders. Conclusion: Cd levels in the bodies of workers in the battery industry serves as a reliable biomarker of Cd exposure, and are closely related to the number of effect biomarkers that can contribute to kidney disorders. This study emphasizes the importance of monitoring Cd exposure levels among workers in the battery industry.
KW - battery industry
KW - effect biomarkers
KW - health risk
KW - kidney disorder
KW - workers’ characteristics
UR - http://www.scopus.com/inward/record.url?scp=85175086856&partnerID=8YFLogxK
U2 - 10.20473/ijosh.v12i2.2023.304-312
DO - 10.20473/ijosh.v12i2.2023.304-312
M3 - Review article
AN - SCOPUS:85175086856
SN - 2301-8046
VL - 12
SP - 304
EP - 312
JO - Indonesian Journal of Occupational Safety and Health
JF - Indonesian Journal of Occupational Safety and Health
IS - 2
ER -