Assessment of Topical and Transdermal Penetration of Curcuma heyneana Rhizome Extract in Rat Skin: Histological Analysis

Idha Kusumawati, Rohmania, Mega Ferdina Warsito, Eka Pramyrtha Hestianah

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Currently, there are increasing numbers of dermal and transdermal dosage forms of both natural and synthetic compounds on the market. Therefore, it is necessary to have a method that can measure the release and penetration of the compound into the skin. This chapter presents a current method for evaluating the skin penetration of a Curcuma heyneana rhizome extract in vivo using histological parameters. We also evaluate a liposome delivery system of the same extract to determine any differences in penetration due to changes in the drug delivery system.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages299-307
Number of pages9
DOIs
Publication statusPublished - 2022

Publication series

NameMethods in Molecular Biology
Volume2343
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Curcuma heyneana rhizome extract
  • Histological analysis
  • Liposomes
  • Skin penetration
  • Skin permeation

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