Antioxidant effect of red dragon fruit peel (Hylocereus polyrhizus) extract in chronic periodontitis rats

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14 Citations (Scopus)

Abstract

The aim of this study is to prove the effect of red dragon fruit (Hylocereus polyrhizus) peel extract on decrease malondyaldehyde level of gingival tissue in chronic periodontitis rats. The experiment was held by post test only control group design. Wistar rats divided into 9 groups. K-is control group of healthy rats, K+ is control group of periodontitis rats given Sodium Carboxymethyl Cellulose (CMC-Na) and P is treatment group of periodontitis rats given gel of red dragon fruit extract for 3 days and 7 days with concentration P1 (1 mg/mL/day), P2 (2 mg/mL/day), and P3 (4 mg/mL/day). After treatment, the rats were sacrificed and gingival tissues malondyaldehyde level of each group was measured by thiobarbituric acid (MDA-TBA) method. The result of data were analyzed using one way ANOVA (p<0,05). The study showed significant decrease on MDA level by 4 mg/mL concentration at 3 days (p<0,05) and significant decrease on MDA levels by 1 mg/mL, 2 mg/mL, and 4 mg/mL concentration at 7 days (p<0,05). The conclusion that the red dragon fruit peel extract can decrease malondialdehyde levels of gingival tissues in chronic periodontitis rats.

Original languageEnglish
Pages (from-to)1363-1367
Number of pages5
JournalJournal of International Dental and Medical Research
Volume12
Issue number4
Publication statusPublished - 2019

Keywords

  • Chronic periodontitis
  • Hylocereus polyrhizus
  • Malondialdehyde

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