TY - JOUR
T1 - Antioxidant effect of red dragon fruit peel (Hylocereus polyrhizus) extract in chronic periodontitis rats
AU - Budi, Hendrik Setia
AU - Juliastuti, Wisnu Setyari
AU - Pitaloka, Ni Putu Clara
N1 - Publisher Copyright:
© 2019 University of Dicle.
PY - 2019
Y1 - 2019
N2 - The aim of this study is to prove the effect of red dragon fruit (Hylocereus polyrhizus) peel extract on decrease malondyaldehyde level of gingival tissue in chronic periodontitis rats. The experiment was held by post test only control group design. Wistar rats divided into 9 groups. K-is control group of healthy rats, K+ is control group of periodontitis rats given Sodium Carboxymethyl Cellulose (CMC-Na) and P is treatment group of periodontitis rats given gel of red dragon fruit extract for 3 days and 7 days with concentration P1 (1 mg/mL/day), P2 (2 mg/mL/day), and P3 (4 mg/mL/day). After treatment, the rats were sacrificed and gingival tissues malondyaldehyde level of each group was measured by thiobarbituric acid (MDA-TBA) method. The result of data were analyzed using one way ANOVA (p<0,05). The study showed significant decrease on MDA level by 4 mg/mL concentration at 3 days (p<0,05) and significant decrease on MDA levels by 1 mg/mL, 2 mg/mL, and 4 mg/mL concentration at 7 days (p<0,05). The conclusion that the red dragon fruit peel extract can decrease malondialdehyde levels of gingival tissues in chronic periodontitis rats.
AB - The aim of this study is to prove the effect of red dragon fruit (Hylocereus polyrhizus) peel extract on decrease malondyaldehyde level of gingival tissue in chronic periodontitis rats. The experiment was held by post test only control group design. Wistar rats divided into 9 groups. K-is control group of healthy rats, K+ is control group of periodontitis rats given Sodium Carboxymethyl Cellulose (CMC-Na) and P is treatment group of periodontitis rats given gel of red dragon fruit extract for 3 days and 7 days with concentration P1 (1 mg/mL/day), P2 (2 mg/mL/day), and P3 (4 mg/mL/day). After treatment, the rats were sacrificed and gingival tissues malondyaldehyde level of each group was measured by thiobarbituric acid (MDA-TBA) method. The result of data were analyzed using one way ANOVA (p<0,05). The study showed significant decrease on MDA level by 4 mg/mL concentration at 3 days (p<0,05) and significant decrease on MDA levels by 1 mg/mL, 2 mg/mL, and 4 mg/mL concentration at 7 days (p<0,05). The conclusion that the red dragon fruit peel extract can decrease malondialdehyde levels of gingival tissues in chronic periodontitis rats.
KW - Chronic periodontitis
KW - Hylocereus polyrhizus
KW - Malondialdehyde
UR - http://www.scopus.com/inward/record.url?scp=85078670388&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85078670388
SN - 1309-100X
VL - 12
SP - 1363
EP - 1367
JO - Journal of International Dental and Medical Research
JF - Journal of International Dental and Medical Research
IS - 4
ER -