TY - JOUR
T1 - Antioxidant activity of flavonoid compounds from the leaves of Macaranga gigantea
AU - Aminah, Nanik Siti
AU - Kristanti, Alfinda Novi
AU - Tanjung, Mulyadi
N1 - Publisher Copyright:
© 2014, Journal of Chemical and Pharmaceutical Research. All Rights Reserved.
PY - 2014
Y1 - 2014
N2 - Three flavonoid compounds have been isolated from the leaves of Macaranga gigantea (Euphorbiaceae) namely as glyasperin A (1), broussoflavonol F (2), apigenin (3). Their structures were elucidated by spectroscopic methods including UV, IR, HRESIMS, 1D and 2D NMR analysis. Compounds 1–3 were evaluated for their radical scavenging against 2,2-diphenyl-1-picrylhydrazyl (DPPH), showing their IC50 were 125.10, 708.54, and 518.01 μM, respectively. The results indicate that as glyasperin A (1) more active than ascorbic acid (329.01 μM).
AB - Three flavonoid compounds have been isolated from the leaves of Macaranga gigantea (Euphorbiaceae) namely as glyasperin A (1), broussoflavonol F (2), apigenin (3). Their structures were elucidated by spectroscopic methods including UV, IR, HRESIMS, 1D and 2D NMR analysis. Compounds 1–3 were evaluated for their radical scavenging against 2,2-diphenyl-1-picrylhydrazyl (DPPH), showing their IC50 were 125.10, 708.54, and 518.01 μM, respectively. The results indicate that as glyasperin A (1) more active than ascorbic acid (329.01 μM).
KW - Antioxidant
KW - Apigenin
KW - Broussoflavonol F
KW - Flavonoid
KW - Glyasperin A
KW - Macaranga gigantea
UR - http://www.scopus.com/inward/record.url?scp=84907241790&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:84907241790
SN - 0975-7384
VL - 6
SP - 688
EP - 692
JO - Journal of Chemical and Pharmaceutical Research
JF - Journal of Chemical and Pharmaceutical Research
IS - 6
ER -