Antimicrobial Susceptibility Test of α-Mangostin against Peptostreptococcus Bacteria

Aim: To determine the antibacterial effect of α-mangostin on the growth of Peptostreptococcus. Materials and methods: This study was included in a laboratory experimental study with a posttest-only control group design using three groups—the positive control group with amoxicillin administration, the negative control group with aquades administration, and the treatment groups by giving α-mangostin at eight different concentrations. Results: The 100% concentration α-mangostin group was the treatment group with the best results in inhibiting the growth of Peptostreptococcus bacteria, but those results were still below the positive control group using amoxicillin. Conclusion: α-mangostin has the potential as an additional alternative medicine to reduce the amount of growth of Peptostreptococcus. Clinical significance: The overall results of this study indicate that α-mangostin with a concentration of 100% can be used as an additional drug in the tooth socket which acts as an antibiotic after tooth extraction because the area of inhibition zone exceeds 18 mm and is included in the sensitivity category.