Antifungal and antibacterial activity of black betel (Piper betle L. var Nigra) extract

Nabilah Istighfari Zuraidassanaaz; Lilis Sulistyorini

Antifungal and antibacterial activity of black betel (Piper betle L. var Nigra) extract

Junairiah, Ni’matuzahroh, Nabilah Istighfari Zuraidassanaaz, Lilis Sulistyorini

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Black betel (Piper betle L. var Nigra) belong to Piperaceae family and one of endemic species of Indonesia. This study was aimed to determine antifungal and antibacterial activity of n-hexane, ethyl acetate, and methanol extracts of Piper betle L. var Nigra toward pathogenic microbes Candida albicans ATCC 10231, Staphylococcus aureus ATCC 25923, and Escherichia coli ATCC 25922. Leaf powder of black betel was macerated using n-hexane, ethyl acetate, and methanol solvents. Antifungal and antibacterial activity was determined using diffusion and dilution tests. Data collected from both tests including diameter of inhibition zone (mm) and Minimal Inhibitory Concentration (MIC), Minimal Bactericidal Concentration (MBC), Minimal Fungicidal Concentration. Data was then analyzed statistically. Result showed that methanol extract of black betel had the highest inhibition activity compared to n-hexane and ethyl acetate extract.

Original language	English
Pages (from-to)	750-755
Number of pages	6
Journal	Bioscience Research
Volume	14
Issue number	4
Publication status	Published - 1 Oct 2017

Keywords

Antibacterial
Antifungal
Piper betle L. var Nigra

Cite this

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abstract = "Black betel (Piper betle L. var Nigra) belong to Piperaceae family and one of endemic species of Indonesia. This study was aimed to determine antifungal and antibacterial activity of n-hexane, ethyl acetate, and methanol extracts of Piper betle L. var Nigra toward pathogenic microbes Candida albicans ATCC 10231, Staphylococcus aureus ATCC 25923, and Escherichia coli ATCC 25922. Leaf powder of black betel was macerated using n-hexane, ethyl acetate, and methanol solvents. Antifungal and antibacterial activity was determined using diffusion and dilution tests. Data collected from both tests including diameter of inhibition zone (mm) and Minimal Inhibitory Concentration (MIC), Minimal Bactericidal Concentration (MBC), Minimal Fungicidal Concentration. Data was then analyzed statistically. Result showed that methanol extract of black betel had the highest inhibition activity compared to n-hexane and ethyl acetate extract.",

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T1 - Antifungal and antibacterial activity of black betel (Piper betle L. var Nigra) extract

AU - Junairiah,

AU - Ni’matuzahroh,

AU - Zuraidassanaaz, Nabilah Istighfari

AU - Sulistyorini, Lilis

PY - 2017/10/1

Y1 - 2017/10/1

N2 - Black betel (Piper betle L. var Nigra) belong to Piperaceae family and one of endemic species of Indonesia. This study was aimed to determine antifungal and antibacterial activity of n-hexane, ethyl acetate, and methanol extracts of Piper betle L. var Nigra toward pathogenic microbes Candida albicans ATCC 10231, Staphylococcus aureus ATCC 25923, and Escherichia coli ATCC 25922. Leaf powder of black betel was macerated using n-hexane, ethyl acetate, and methanol solvents. Antifungal and antibacterial activity was determined using diffusion and dilution tests. Data collected from both tests including diameter of inhibition zone (mm) and Minimal Inhibitory Concentration (MIC), Minimal Bactericidal Concentration (MBC), Minimal Fungicidal Concentration. Data was then analyzed statistically. Result showed that methanol extract of black betel had the highest inhibition activity compared to n-hexane and ethyl acetate extract.

AB - Black betel (Piper betle L. var Nigra) belong to Piperaceae family and one of endemic species of Indonesia. This study was aimed to determine antifungal and antibacterial activity of n-hexane, ethyl acetate, and methanol extracts of Piper betle L. var Nigra toward pathogenic microbes Candida albicans ATCC 10231, Staphylococcus aureus ATCC 25923, and Escherichia coli ATCC 25922. Leaf powder of black betel was macerated using n-hexane, ethyl acetate, and methanol solvents. Antifungal and antibacterial activity was determined using diffusion and dilution tests. Data collected from both tests including diameter of inhibition zone (mm) and Minimal Inhibitory Concentration (MIC), Minimal Bactericidal Concentration (MBC), Minimal Fungicidal Concentration. Data was then analyzed statistically. Result showed that methanol extract of black betel had the highest inhibition activity compared to n-hexane and ethyl acetate extract.

KW - Antibacterial

KW - Antifungal

KW - Piper betle L. var Nigra

UR - http://www.scopus.com/inward/record.url?scp=85040174380&partnerID=8YFLogxK

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SN - 1811-9506

VL - 14

SP - 750

EP - 755

JO - Bioscience Research

JF - Bioscience Research

IS - 4

ER -

Antifungal and antibacterial activity of black betel (Piper betle L. var Nigra) extract

Abstract

Keywords

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