Antifungal Activity of silver loaded zeolite a from bagasse ash against candida albicans

Alfa A. Widati, Afaf Baktir, Ryan Rachmawan

Research output: Contribution to journalArticlepeer-review

Abstract

Normally, Candida albicans is found in the gastrointestinal tract, the upper respiratory tract and the genital mucosa of mammals. Candida albicans can form biofilm because of the increasing population and the resistance of the existing antifungal. Silver loaded zeolite A is an anti-fungal material that is effective in inhibiting the pathogen microorganism. This study aims to demonstrate the preparation of silver loaded zeolite A from bagasse ash and its antifungal activity against Candida albicans. Silver loaded zeolite A was obtained by ion exchange mechanism on zeolite A. It was characterized using XRD and XRF. The inhibition of the growth of Candida albicans by silver loaded zeolite A was observed from cell viability of Candida albicans. The optimum concentration of silver loaded zeolite A to inhibit the growth of Candida albicans was 4.5 g/L at 60 hours. This inhibition mechanism was resulted from the releasing of silver from zeolite A.

Original languageEnglish
Pages (from-to)14-19
Number of pages6
JournalChemist
Volume90
Issue number1
Publication statusPublished - 2017

Keywords

  • Antifungal
  • Bagasse ash
  • Candida albicans
  • Silver loaded zeolite A
  • Viability cell

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