TY - JOUR
T1 - Antidiabetic Activity of Ketapang (Terminalia catappa L.) Leaves Extract in Streptozotocin-Induced Diabetic Mice
AU - Hayaza, Suhailah
AU - Istiqomah, Siti
AU - Kuncoroningrat Susilo, Raden Joko
AU - Inayatillah, Bilqis
AU - Ansori, Arif Nur Muhammad
AU - Winarni, Dwi
AU - Husen, Saikhu Akhmad
AU - Darmanto, Win
N1 - Publisher Copyright:
© 2019 Indian Veterinary Assocaition. All rights reserved.
PY - 2019
Y1 - 2019
N2 - This study aims to determine the effect of Ketapang leaves crude extract (KLCE) on diabetic mice. Mice were divided into 6 groups: KN (normal), KD (negative control), KM (positive control; given 6.5 mg/kg metformin), and KP1 (treatment group, were given 50 mg of KLCE), KP2 (100 mg of KLCE), and KP3 (200 mg body weight of KLCE) per kg. Body weight fasting blood glucose level, tissue glucose tolerance, and Langerhans islet diameters were analyzed. The results showed that the administration of KLCE could increase mice's body weight, tissue glucose tolerance, Langerhans islet diameter, and reduce fasting blood glucose level.
AB - This study aims to determine the effect of Ketapang leaves crude extract (KLCE) on diabetic mice. Mice were divided into 6 groups: KN (normal), KD (negative control), KM (positive control; given 6.5 mg/kg metformin), and KP1 (treatment group, were given 50 mg of KLCE), KP2 (100 mg of KLCE), and KP3 (200 mg body weight of KLCE) per kg. Body weight fasting blood glucose level, tissue glucose tolerance, and Langerhans islet diameters were analyzed. The results showed that the administration of KLCE could increase mice's body weight, tissue glucose tolerance, Langerhans islet diameter, and reduce fasting blood glucose level.
KW - Antidiabetic
KW - Diabetic mice
KW - Strep-tozotocin
KW - Terminalia catappa L
UR - http://www.scopus.com/inward/record.url?scp=85078168251&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85078168251
SN - 0019-6479
VL - 96
SP - 11
EP - 13
JO - Indian Veterinary Journal
JF - Indian Veterinary Journal
IS - 12
ER -