Anti-inflammatory effect of okra (Abelmoschus esculentus) fruit extract during wound healing process after tooth extraction of diabetic wistar rat

To analyze the anti-inflammatory properties of okra fruit extract and its efffect toward wound healing process in diabetic mellitus rats. 27 Wistar rats were divided into three groups: (1) negative control (K-), (2) positive control (K+) and (3) streptozotocin induction and 250 mg/kg body weight okra fruit extract (P). Three rats from each group were sacrificed on the 1st, 4th, and 7th days after extraction of their left lower incisor and excised for histologic examination by Hematoxylin Eosin (HE) staining to enable evaluation of the neutrophil expressions. The administration of okra extract to the tooth extraction wounds significantly reduced neutrophil expression compared to that in the untreated group. There was a significant difference on day 1 between the following groups: (1) K- and K+ and (2) K + and P. On day 4, the most significant difference was between K- and P. On day 7, the most significant difference was between K- and K+ group, K+ and P group. Okra fruit extract exhibits anti-inflammatory activity and is, therefore, an effective agent for healing process of tooth extraction wounds in diabetic mellitus rats.