TY - JOUR
T1 - Anthropometry-based body fat percentage predicts high hs-CRP in chronic kidney disease patients
AU - Thaha, Mochammad
AU - Empitu, Maulana Antiyan
AU - Kadariswantiningsih, Ika Nindya
AU - Nugroho, Cahyo Wibisono
AU - Hasanatuludhhiyah, Nurina
AU - Rasyid, Haerani
AU - Hakim, Zaky El
AU - Suryansyah, Maulana Muhtadin
AU - Alda, Rieza Rizqi
AU - Alsagaff, Mohammad Yusuf
AU - Amin, Mochammad
AU - Santoso, Djoko
AU - Suzuki, Yusuke
N1 - Publisher Copyright:
© Prodia Education and Research Institute.
PY - 2018
Y1 - 2018
N2 - BACKGROUND: Obesity is an important cardiovascular risk factor and associated with low grade inflammation in chronic kidney disease (CKD) patients. This study aims to assess the association between body fat with serum high sensitivity C-reactive protein (hs-CRP) level in CKD patients. METHODS: A cross-sectional study was performed in 71 CKD patients. Anthropometric measurements included body weight, height, body mass index (BMI), body fat percentage (BFP), skinfold thickness (SKF) of triceps and biceps were performed by trained physician. BFP was calculated using Kwok's Formula and hs-CRP was measured by Particle enhanced Turbidimetry. RESULTS: The averaged BMI of our subjects was 25.8±4.4. There was no significant difference in BMI between pre-dialysis and hemodialysis CKD patients. Positive correlation was found between BFP and hs-CRP (r=0.266; p < 0.05), while there was no significant correlation between BMI and hs-CRP. CONCLUSION: Body fat percentage was associated with hs-CRP. Hence, it will be more beneficial to assess nutritional status in CKD using BFP rather than BMI alone since it was demonstrated to correlate with hs-CRP in our study.
AB - BACKGROUND: Obesity is an important cardiovascular risk factor and associated with low grade inflammation in chronic kidney disease (CKD) patients. This study aims to assess the association between body fat with serum high sensitivity C-reactive protein (hs-CRP) level in CKD patients. METHODS: A cross-sectional study was performed in 71 CKD patients. Anthropometric measurements included body weight, height, body mass index (BMI), body fat percentage (BFP), skinfold thickness (SKF) of triceps and biceps were performed by trained physician. BFP was calculated using Kwok's Formula and hs-CRP was measured by Particle enhanced Turbidimetry. RESULTS: The averaged BMI of our subjects was 25.8±4.4. There was no significant difference in BMI between pre-dialysis and hemodialysis CKD patients. Positive correlation was found between BFP and hs-CRP (r=0.266; p < 0.05), while there was no significant correlation between BMI and hs-CRP. CONCLUSION: Body fat percentage was associated with hs-CRP. Hence, it will be more beneficial to assess nutritional status in CKD using BFP rather than BMI alone since it was demonstrated to correlate with hs-CRP in our study.
KW - Body fat
KW - CKD
KW - Hs-CRP
KW - Inflammation
KW - Obesity
UR - http://www.scopus.com/inward/record.url?scp=85051579486&partnerID=8YFLogxK
U2 - 10.18585/inabj.v10i2.397
DO - 10.18585/inabj.v10i2.397
M3 - Article
AN - SCOPUS:85051579486
SN - 2085-3297
VL - 10
SP - 184
EP - 191
JO - Indonesian Biomedical Journal
JF - Indonesian Biomedical Journal
IS - 2
ER -
