The development of carbon paste electrodes modified with the molecularly imprinted polymer (MIP) for the potentiometric analysis of uric acid was carried out in this study. MIP was made from methyl methacrylate as a monomer, ethylene glycol dimethacrylate as crosslinker, and uric acid as a template. The carbon paste electrodes/MIP is produced from carbon, MIP, and paraffin with ratio 40: 25: 35 (%, w/w). The measurement of uric acid with carbon paste electrodes/MIP produced Nernst factor of 30.19 mV/decade with a measurement range of 10-6-10-3 M. The minimum detection limit of this method was 3.03.10-6 M, the precision and accuracy towards uric acid with a concentration of 10-6-10-3 M was ranging between 1.36-2.03% and 63.9-166%. The selectivity coefficient value was less than one which indicated that the electrode was selective against uric acid and was not interfered by urea. This electrode has a response time less than two minutes and lifetime is eight weeks with the usage is 104 times.
- Carbon paste electrodes
- Molecularly imprinted polymer
- Uric acid