TY - JOUR
T1 - Analysis of Sibling Pair Relationships of Balineses Indonesia, Using 12 STR Loci for Human Identification Process
AU - Furqoni, Abdul Hadi
AU - Palupi, Retno
AU - Yudianto, Ahmad
AU - Sosiawan, Agung
AU - Tirthaningsih, Ni Wajan
AU - Fore, Faith
AU - Setyowati, Dewi
N1 - Funding Information:
Our acknowledgements go to the Human Genetic Laboratory at Tropical Diseases Centre, Universitas Airlangga and Founding Research mandate of Universitas Airlangga for their unending support during the course of this research.
Publisher Copyright:
© 2021. All rights reserved.
PY - 2021
Y1 - 2021
N2 - Use of STR locus in studying the relations between siblings for the need of ethnic genetic database in Indonesia for identifying disaster victims, criminals and Probation Test (paternity test) is not well established compared to other countries. Targeted outcomes are STR typing and profiling of the human genome for individual identification and kin relations. The aim of this study was to analyse kin relationships among siblings by assessing and determining a better STR locus and the level of allelic distribution among full siblings in Balinese people of Indonesia. From a collection of 10 Balinese families, we took a sample of 4 people for each family consisting of the father, mother, and two children. Kin relationships were analysed by using 13 STR loci technique (CSF1PO, F13B, FES, TH01, TPOX, VWA, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, and D21S11). Through the use of 13 autosomal STR loci, this study provides evidence that the strength of sharing 2 alleles can be used as a reference in that siblings have high kinship relations. Based on the results of this study, STR loci D8S1179 and S21S11 are recommended when typing the Balinese.
AB - Use of STR locus in studying the relations between siblings for the need of ethnic genetic database in Indonesia for identifying disaster victims, criminals and Probation Test (paternity test) is not well established compared to other countries. Targeted outcomes are STR typing and profiling of the human genome for individual identification and kin relations. The aim of this study was to analyse kin relationships among siblings by assessing and determining a better STR locus and the level of allelic distribution among full siblings in Balinese people of Indonesia. From a collection of 10 Balinese families, we took a sample of 4 people for each family consisting of the father, mother, and two children. Kin relationships were analysed by using 13 STR loci technique (CSF1PO, F13B, FES, TH01, TPOX, VWA, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, and D21S11). Through the use of 13 autosomal STR loci, this study provides evidence that the strength of sharing 2 alleles can be used as a reference in that siblings have high kinship relations. Based on the results of this study, STR loci D8S1179 and S21S11 are recommended when typing the Balinese.
KW - Balinese
KW - kinship
KW - loci
KW - Siblings
KW - STR
UR - http://www.scopus.com/inward/record.url?scp=85110669217&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85110669217
SN - 1309-100X
VL - 14
SP - 855
EP - 859
JO - Journal of International Dental and Medical Research
JF - Journal of International Dental and Medical Research
IS - 2
ER -