Analysis of glucose by potentiometry using electrode carbon paste/molecularly imprinted polymer (MIP) with metacrylic acid as monomer

The electrode carbon paste molecularly imprinted polymer (MIP) has been developed to analyze glucose by potentiometry. The MIP was made by mixing glucose as a template, methacrylic acid as monomer and ethylene glycol dimethacrylate as a crosslinker with the mole ratio of 1: 4: 12. The electrode made by mixing activated carbon, MIP, and paraffin with the ratio 50: 35: 15 (%, w/w) was observed to perform optimally. The results obtained show that analysis of glucose gives optimum results at pH 5 (without the pH adjustment). The analysis of glucose using electrodes carbon paste/MIP gives Nernst factor is 28.80 mV/decade, the measurement range is 10^-2 - 10^-5 M and the limit of detection is 5.87.10^-5 M. In this study can be known that urea did not interfere the analysis of glucose using this method. The accuracy of this electrode is 70.7 - 129% and the coefficient of variation is 0.06 - 0.18% for the concentration range 10^-5 - 10^-2 M. This electrode showed response time less than 2 minutes and could be used for 145 times.