TY - JOUR
T1 - An Indonesian male with congenital hypogonadotropic hypogonadism
T2 - A case report and literature review
AU - Arrosy, Leadri Surya
AU - Novida, Hermina
N1 - Publisher Copyright:
© 2022 The Authors
PY - 2022/10
Y1 - 2022/10
N2 - Introduction: Congenital hypogonadotropic hypogonadism (CHH) is a rare disorder caused by insufficient gonadotropin-releasing hormone (GnRH) production. Case presentation: An Indonesian adolescent, 22 years old, Javanese ethnic, complained of a small penis, low sexual desire, fatigue, and anosmia since childhood. Medical history stated that the patient had low testosterone levels 7 years ago and received testosterone once. Testosterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) were decreased. The testicular ultrasound result was bilateral microtestis, suspicious of bilateral hypoplasia of the epididymis. Brain MRI also supports the diagnosis of hypogonadotropic hypogonadism, and the patient received Sustanon of 250 mg/2 weeks. The patient showed a good prognosis after 1 month of therapy. Discussion: The success of CHH therapy must be explored to improve its management. Conclusion: CHH in an Indonesian male shows a good prognosis with testosterone injection.
AB - Introduction: Congenital hypogonadotropic hypogonadism (CHH) is a rare disorder caused by insufficient gonadotropin-releasing hormone (GnRH) production. Case presentation: An Indonesian adolescent, 22 years old, Javanese ethnic, complained of a small penis, low sexual desire, fatigue, and anosmia since childhood. Medical history stated that the patient had low testosterone levels 7 years ago and received testosterone once. Testosterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) were decreased. The testicular ultrasound result was bilateral microtestis, suspicious of bilateral hypoplasia of the epididymis. Brain MRI also supports the diagnosis of hypogonadotropic hypogonadism, and the patient received Sustanon of 250 mg/2 weeks. The patient showed a good prognosis after 1 month of therapy. Discussion: The success of CHH therapy must be explored to improve its management. Conclusion: CHH in an Indonesian male shows a good prognosis with testosterone injection.
KW - Congenital hypogonadotropic hypogonadism
KW - Follicle-stimulating hormone
KW - Luteinizing hormone
KW - Testosterone
UR - http://www.scopus.com/inward/record.url?scp=85138593504&partnerID=8YFLogxK
U2 - 10.1016/j.amsu.2022.104720
DO - 10.1016/j.amsu.2022.104720
M3 - Article
AN - SCOPUS:85138593504
SN - 2049-0801
VL - 82
JO - Annals of Medicine and Surgery
JF - Annals of Medicine and Surgery
M1 - 104720
ER -