TY - JOUR
T1 - An Indonesian female with Stevens-Johnson syndrome mimicking cutaneous lupus
T2 - A case report
AU - Samson, Nadya Meilinar
AU - Awalia,
N1 - Publisher Copyright:
© 2022 The Authors
PY - 2022/10
Y1 - 2022/10
N2 - Background: Diagnosing bullous eruptions in systemic lupus erythematosus (SLE) patients is challenging because there are so many differential diagnoses, including drug reactions such as Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and TEN-like cutaneous lupus erythematosus (LE). Case presentation: An Indonesian female with a SLE history complained of an erythematous rash over the body 2 weeks ago. A pulse dose of methylprednisolone was given, and after 3 days, of getting bullae appeared all over the body and treatment stopped. The patient is treated in collaboration with dermatology, ophthalmology, and allergy consultants to obtain a diagnosis of SJS supporting skin biopsy. The patient was given methylprednisolone 62.5 mg once daily for 7 days, Gentamicin 80 mg twice daily, and the skin lesion was treated with NaCl 0.9% compression. The patient showed improvement and decreased methylprednisolone dose to 16 mg 3 times a day. Discussion: Skin biopsy must be obtained to establish the diagnosis between JSJ/TEN and cutaneous LE. Conclusion: SJS/TEN can occur in SLE patients. The correct diagnosis can reduce the patient's mortality and morbidity.
AB - Background: Diagnosing bullous eruptions in systemic lupus erythematosus (SLE) patients is challenging because there are so many differential diagnoses, including drug reactions such as Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and TEN-like cutaneous lupus erythematosus (LE). Case presentation: An Indonesian female with a SLE history complained of an erythematous rash over the body 2 weeks ago. A pulse dose of methylprednisolone was given, and after 3 days, of getting bullae appeared all over the body and treatment stopped. The patient is treated in collaboration with dermatology, ophthalmology, and allergy consultants to obtain a diagnosis of SJS supporting skin biopsy. The patient was given methylprednisolone 62.5 mg once daily for 7 days, Gentamicin 80 mg twice daily, and the skin lesion was treated with NaCl 0.9% compression. The patient showed improvement and decreased methylprednisolone dose to 16 mg 3 times a day. Discussion: Skin biopsy must be obtained to establish the diagnosis between JSJ/TEN and cutaneous LE. Conclusion: SJS/TEN can occur in SLE patients. The correct diagnosis can reduce the patient's mortality and morbidity.
KW - Illness
KW - Lupus erythematosus
KW - Steroid
KW - Stevens-Johnson syndrome
KW - Toxic epidermal necrolysis
UR - http://www.scopus.com/inward/record.url?scp=85138581523&partnerID=8YFLogxK
U2 - 10.1016/j.amsu.2022.104644
DO - 10.1016/j.amsu.2022.104644
M3 - Article
AN - SCOPUS:85138581523
SN - 2049-0801
VL - 82
JO - Annals of Medicine and Surgery
JF - Annals of Medicine and Surgery
M1 - 104644
ER -