Aluminosilicates decrease cytochrome-c and caspase-3 expression in mice uterine glands model zearalenone intoxication

This study aimed to examine the aluminosilicates to eliminate zearalenone on the expression of cytochrome-c and caspase-3 in mice uterine glands. We used 20 mice balb/c strain and randomly divided into 5 groups. Negative control (C-) weren't treated neither with zearalenone nor aluminosilicates, positive control (C+) were treated with 0.1 mg/mice/day Zearalenone, T1; T2; and T3 were treated with a dose of 0.1 mg/mice/day zearalenone and (0.5; 1; 2) mg/mice/day aluminosilicates, respectively. The data analyzed by ANOVA then followed by Duncan test. The cytochrome-c and caspase-3 expression were not different between C+ and T3 groups. It can be concluded that dose of 2 mg/mice/day aluminosilicates decreased the zearalenone intoxication.