Albuminuria as a risk factor for diabetic retinopathy in indonesian type 2 diabetes mellitus patients

Soebagijo Adi Soelistijo, Deasy Ardiany, Robert Dwitama Adiwinoto, Agung Pranoto, Sauli Ari Widjaja

Research output: Contribution to journalArticlepeer-review

Abstract

Diabetic retinopathy (DR) is the leading cause of new-onset blindness in productive age. The aim of the study is to investigate the clinical relevance of albuminuria as a risk factor for DR in Indonesian Type 2 Diabetes Mellitus (T2DM) patients, as both have similar pathogenesis and are closely related. A number of 168 adult T2DM patients in the diabetes outpatient clinic at the Dr. Soetomo General Academic Hospital were recruited from July to December 2019 for this cross-sectional study. All participants underwent complete history taking and physical examination. A comprehensive metabolic panel and urinalysis parameters were collected from all subjects. Bivariate analysis with the chi-square test was used, followed by multivariate analysis by logistic regression. Albuminuria and DR were present in 125 subjects (74.4%) and 80 subjects (47.6%) respectively. There was a statistically significant difference in the prevalence of albuminuria between the group with and without DR (p=0.000). Through multivariate logistic regression, the presence of albuminuria increased the risk for DR 4.857 folds (95% CI: 2.029–11.626; p=0.000) adjusted for age, sex, BMI, systolic blood pressure, diastolic blood pressure, HbA1c levels, and dyslipidemia. In conclusion, albuminuria increases the risk of developing DR in Indonesian T2DM patients.

Original languageEnglish
Pages (from-to)170-175
Number of pages6
JournalRomanian Journal of Diabetes, Nutrition and Metabolic Diseases
Volume31
Issue number2
DOIs
Publication statusPublished - 2024
Externally publishedYes

Keywords

  • albuminuria
  • diabetic nephropathy
  • diabetic retinopathy
  • type 2 diabetes

Fingerprint

Dive into the research topics of 'Albuminuria as a risk factor for diabetic retinopathy in indonesian type 2 diabetes mellitus patients'. Together they form a unique fingerprint.

Cite this