Alasmontamine A, A first tetrakis monoterpene indole alkaloid from Tabernaemontana elegans

Yusuke Hirasawa, Saori Miyama, Takahiro Hosoya, Koichiro Koyama, Abdul Rahman, Idha Kusumawati, Noor Cholies Zaini, Hiroshi Morita

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)

Abstract

[Chemical Equation Presented] A novel tetrakis monoterpene indole alkaloid, alasmontamine A (1) consisting of bis-vobtusine-type skeletons, was isolated from the leaves of Tabernaemontana elegans. The structure including the relative stereochemistry was elucidated on the basis of spectroscopic data. Alasmontamine A (1) exhibited moderate cell growth inhibitory activity against HL-60 cells.

Original languageEnglish
Pages (from-to)5718-5721
Number of pages4
JournalOrganic Letters
Volume11
Issue number24
DOIs
Publication statusPublished - 17 Dec 2009

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