TY - JOUR
T1 - Adult Patients with Aphallia
T2 - Were they Fertile?
AU - Sisca, Eni Maria
AU - Pakpahan, Cennikon
AU - Rezano, Andri
AU - Margiana, Ria
AU - Agustinus, Agustinus
AU - Tanojo, Tjahjo Djojo
N1 - Publisher Copyright:
© 2022 Eni Maria Sisca, Cennikon Pakpahan, Andri Rezano, Ria Margiana, Agustinus Agustinus and Tjahjo Djojo Tanojo.
PY - 2022
Y1 - 2022
N2 - Adult male genotype and phenotype with aphallia are men born without a penis. The effectiveness of male sex assignment or female sex reassignment as a treatment for aphallia has been debated. The study's goal was to address the gonadal existence and supporting investigation related to the reproductive health care of reported cases of aphallia patients such as karyotyping, physical examination, semen analysis, hormone reproduction level, sperm retrieval, radiological investigation type of intervention. In this narrative review, data were obtained from Pubmed and Google Scholar that contains keywords “absence penis", "penile agenesis”, “phalloplasty” “fertility function”. We excluded pediatric patients with aphallia or adult patients with aphallia that reassignments to be female. Only five of the case reports were adult patients with aphallia that reported their fertility function and remains the gonadal existence. All samples have fertility potential disregard their aphallia based on primary testicular function, semen analysis, hormonal profile radiological investigation. Radiology supporting to the investigation of fertility function has aimed to detect genitourinary anomaly related to the site of urinary meatus associated with death rate. Four patients showed post sphincteric meatus urinary and one patient was presphincteric meatus urinary. Gonadal existence is addressed in the case report. This report suggested that sex assignment on aphallia patients should be considered based on the gonadal existence because even though they do not have a penis, they can have children through assisted reproductive technology provided that their phenotype and genotype are matched.
AB - Adult male genotype and phenotype with aphallia are men born without a penis. The effectiveness of male sex assignment or female sex reassignment as a treatment for aphallia has been debated. The study's goal was to address the gonadal existence and supporting investigation related to the reproductive health care of reported cases of aphallia patients such as karyotyping, physical examination, semen analysis, hormone reproduction level, sperm retrieval, radiological investigation type of intervention. In this narrative review, data were obtained from Pubmed and Google Scholar that contains keywords “absence penis", "penile agenesis”, “phalloplasty” “fertility function”. We excluded pediatric patients with aphallia or adult patients with aphallia that reassignments to be female. Only five of the case reports were adult patients with aphallia that reported their fertility function and remains the gonadal existence. All samples have fertility potential disregard their aphallia based on primary testicular function, semen analysis, hormonal profile radiological investigation. Radiology supporting to the investigation of fertility function has aimed to detect genitourinary anomaly related to the site of urinary meatus associated with death rate. Four patients showed post sphincteric meatus urinary and one patient was presphincteric meatus urinary. Gonadal existence is addressed in the case report. This report suggested that sex assignment on aphallia patients should be considered based on the gonadal existence because even though they do not have a penis, they can have children through assisted reproductive technology provided that their phenotype and genotype are matched.
KW - Absence Penis
KW - Fertility Function
KW - Gonadal Existence
KW - Penile Agenesis
KW - Phalloplasty
KW - Reproductive Health Care
KW - Sex Reassignment
UR - http://www.scopus.com/inward/record.url?scp=85131558025&partnerID=8YFLogxK
U2 - 10.3844/ojbsci.2022.214.222
DO - 10.3844/ojbsci.2022.214.222
M3 - Article
AN - SCOPUS:85131558025
SN - 1608-4217
VL - 22
SP - 214
EP - 222
JO - OnLine Journal of Biological Sciences
JF - OnLine Journal of Biological Sciences
IS - 2
ER -